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Gene Page - CG Number : CG10021
Gene Summary - CG10021:

CG10021: The gene brother of odd with entrails limited is referred to in FlyBase by the symbol Dmel\bowl (CG10021, FBgn0004893). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process: terminal region determination; wing disc development; embryonic hindgut morphogenesis; hindgut morphogenesis; lateral inhibition; imaginal disc-derived leg morphogenesis; embryonic foregut morphogenesis; imaginal disc-derived leg joint morphogenesis. 33 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; organ system subdivision; adult segment; embryonic hindgut; embryonic gnathal segment; cephalopharyngeal skeleton; non-connected developing system; appendage segment; larval abdominal segment; acellular anatomical structure. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Zinc finger C2H2-type/integrase DNA-binding domain; Zinc finger, C2H2; Zinc finger, C2H2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.

Gene summary for CG10021 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10021:CG10021 is perturbed in following parameters in primary screen: Tint2
CG10021 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10021.
Cell Count:
CG_NumberCategoryR1R2R3
CG10021Primary screen371697352
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10021:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812040.7857720410.619037010.9201202890.9639322960.2941253260.4997820830.5951186080.5156193191.0550555992.7744842172.496906582-0.5761687021.5293933541.1790329070.9817849720.4124288162.7767330982.2829421852.2215918571.1000427530.2653391030.9644985970.065312859
1821121.648614663-0.554823321-0.7646533481.8036303510.2281431650.1294792030.075880650.1753234291.1207070633.0605846890.702068880.2722567470.8205860760.093502436-0.3549984810.2259654381.7874733874.4197332192.2706516950.7267721130.4645515240.409354899-0.295395191
1832620.6595446481.867117391-0.2989550891.541779997-0.103221628-0.124079107-0.082987389-0.284217855-0.584066268-0.752859333-0.7318682740.225708489-0.535056721-0.74602249-0.076779402-0.52731422-1.69003002-0.855054669-1.772279367-0.415629921.4178668011.4943039140.691391104
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10021 is not tested in classification assay
Integrated Annotations for CG10021 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
hindgut morphogenesisGO:0007442inferred from mutant phenotype
imaginal disc-derived leg joint morphogenesis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity with odd
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding RNA polymerase II transcription factor activityGO:0000981inferred from sequence or structural similarity with odd
zinc ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10021 in FlyBase
FLIGHTClick here to see CG10021 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10021 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10021
Entrez GeneEntrez Gene page for CG10021
UniprotUniprot page for CG10021

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)