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Gene Page - CG Number : CG10037
Gene Summary - CG10037:

CG10037: The gene ventral veins lacking is referred to in FlyBase by the symbol Dmel\vvl (CG10037, FBgn0086680). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: RNA polymerase II regulatory region sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription. There is experimental evidence that it is involved in the biological process: motor neuron axon guidance; regulation of dendrite morphogenesis; positive regulation of transcription from RNA polymerase II promoter; brain development; brain segmentation; peripheral nervous system development. 30 alleles are reported. The phenotypes of these alleles are annotated with 37 unique terms, many of which group under: organ system subdivision; organ system; adult segment; larval abdominal segment; non-connected developing system; sensory cluster; portion of tissue; adult; peripheral nervous system; region of integument. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Homeobox, conserved site; Homeodomain; Homeodomain-like; Lambda repressor-like, DNA-binding domain; POU domain; POU-specific; Transcription factor, homeobox/POU. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages.

Gene summary for CG10037 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10037:CG10037 is not perturbed in primary screen.
CG10037 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10037.
Cell Count:
CG_NumberCategoryR1R2R3
CG10037Primary screen69885623
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10037:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812121.8117402021.555040768-0.5444980330.128740499-2.175041293-2.031344499-2.549580273-3.061210438-2.7280713924.6335640121.5099144273.9786425094.4123499784.8004805123.114280545-0.4377999275.318941273.4397020218.386070459-1.7822466363.632305786-0.10491498-1.57408015
182743.7068723352.3649141111.6468046842.6596327481.5246135551.3481350931.4917550780.9059985330.9196267280.613903451.194541108-0.5558829070.734546430.1456284622.9905668431.0186494921.6403041810.717975111.4068283911.459332892.2857734030.5026609280.736779842
1832240.290875570.014835286-0.5517787930.3334438350.8789992491.3066825970.7116916641.0601158231.6464585110.1909345370.847071073-0.2220080920.827275339-0.0898998691.9594203140.5830864520.8981129082.1866170291.5361338581.658167451-0.3447145242.5281781960.181878233
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10037 is not tested in classification assay
Integrated Annotations for CG10037 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
peripheral nervous system developmentGO:0007422traceable author statement
epithelial cell fate determination, open tracheal system
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity with UniProtKB:Q17237
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
DNA bindingGO:0003677non-traceable author statement
sequence-specific DNA binding transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10037 in FlyBase
FLIGHTClick here to see CG10037 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10037 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10037
Entrez GeneEntrez Gene page for CG10037
UniprotUniprot page for CG10037

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)