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Gene Page - CG Number : CG10042
Gene Summary - CG10042:

CG10042: The gene MBD-R2 is referred to in FlyBase by the symbol Dmel\MBD-R2 (CG10042, FBgn0038016). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; zinc ion binding. There is experimental evidence that it is involved in the biological process: mitotic cell cycle G2/M transition DNA damage checkpoint; neurogenesis. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: DNA-binding, integrase-type; Methyl-CpG DNA binding; Zinc finger, C2CH-type; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, PHD-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during early pupal stages, in stages of adults of both sexes.

Gene summary for CG10042 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10042:CG10042 is not perturbed in primary screen.
CG10042 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10042.
Cell Count:
CG_NumberCategoryR1R2R3
CG10042Primary screen266872674
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10042:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
181216-0.446261904-0.923375024-0.304046920.074186365-0.338478741-0.358468019-0.591959939-0.418241465-0.290105772-0.1503021410.5175722110.4654004840.3012627970.28775695-0.440445332-0.6942450780.169293510.200607014-0.305542599-0.207049468-0.3005559981.7567044181.305180306
182702.2522911570.6431662160.5722563230.6209653420.2607148940.9975137451.2333022081.1393530911.9762488010.343922825-0.628700341.2024712680.9261694280.2123118742.8997449571.1445706270.699967580.2302176540.9931553451.8122894652.415064157-0.14782393-0.226841508
183220-0.1029699550.138161069-0.085927302-0.4059015380.8864769840.7668635760.2313106230.838069910.591321503-0.775868827-0.820051829-0.678145732-0.068972944-1.4112744742.0228082540.878403286-0.422458953-0.294470134-0.3824875920.4121569621.839533489-0.650267756-0.60587127
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10042 is not tested in classification assay
Integrated Annotations for CG10042 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
neurogenesisGO:0022008inferred from mutant phenotype
mitotic cell cycle G2/M transition DNA damage checkpoint
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from direct assay
transcriptionally active chromatin
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
DNA bindingGO:0003677inferred from electronic annotation with InterPro:IPR001739, InterPro:IPR016177
zinc ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10042 in FlyBase
FLIGHTClick here to see CG10042 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10042 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10042
Entrez GeneEntrez Gene page for CG10042
UniprotUniprot page for CG10042

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)