Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG10047
Gene Summary - CG10047:

CG10047: The gene Synaptotagmin 4 is referred to in FlyBase by the symbol Dmel\Syt4 (CG10047, FBgn0028400). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: calcium-dependent phospholipid binding. There is experimental evidence that it is involved in the biological process: regulation of neurotransmitter secretion; regulation of synaptic plasticity. 18 alleles are reported. The phenotypes of these alleles are annotated with: NMJ bouton; neuromuscular junction; motor neuron. It has one annotated transcript and one annotated polypeptide. Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 domain; C2 membrane targeting protein; Synaptotagmin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.

Gene summary for CG10047 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10047:CG10047 is not perturbed in primary screen.
CG10047 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10047.
Cell Count:
CG_NumberCategoryR1R2R3
CG10047Primary screen212977667
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10047:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812202.380746923-0.4520060140.7903827341.651850388-1.306125989-1.850643817-0.45889383-2.226827856-3.569838465-0.628935964-1.847135965-0.390781891-1.558369265-0.878715148-0.260101758-0.429262865-2.10007106-1.711544541-1.799063044-3.212831599-0.262590717-0.0084951090.980776212
182662.193013340.110292678-0.1904187971.3170954231.1546789941.3345400150.7616198381.4473550271.519130675-0.2242253651.597127245-0.3774721760.654392197-0.186848622.1750075761.4197123930.6103628260.5695424990.3312518081.3211919954.3789066220.6286617612.342414396
1832161.8123384771.6248710841.0077020450.6741194280.0052508820.1980411550.4811388430.3188190430.4864648050.138480945-0.800813977-0.248251881-0.630239659-1.1805190730.009803080.547539049-0.492720043-0.2446594250.1772842140.4998661121.5097553940.015446762-0.530790304
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10047 is not tested in classification assay
Integrated Annotations for CG10047 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
neurotransmitter secretionGO:0007269non-traceable author statement
vesicle-mediated transport
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
synaptic vesicleGO:0008021inferred from sequence or structural similarity
plasma membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
calcium-dependent phospholipid bindingGO:0005544non-traceable author statement
transporter activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10047 in FlyBase
FLIGHTClick here to see CG10047 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10047 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10047
Entrez GeneEntrez Gene page for CG10047
UniprotUniprot page for CG10047

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)