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Gene Page - CG Number : CG10067
Gene Summary - CG10067:

CG10067: The gene Actin 57B is referred to in FlyBase by the symbol Dmel\Act57B (CG10067, FBgn0000044). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of cytoskeleton. There is experimental evidence that it is involved in the biological process: centrosome organization; positive regulation of NFAT protein import into nucleus; cytokinesis. 8 alleles are reported. The phenotype of these alleles is annotated with: germline cyst. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Actin, conserved site; Actin-like; Actin/actin-like conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of moderately high expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages.

Gene summary for CG10067 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10067:CG10067 is not perturbed in primary screen.
CG10067 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10067.
Cell Count:
CG_NumberCategoryR1R2R3
CG10067Primary screen524798454
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10067:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
181231-0.256771661-0.413447278-0.524001083-0.4564314470.8541152140.9103339620.1908084430.7664427020.9626087741.2606077810.4240291080.0559525150.6900286460.269282035-0.6473724111.1066440360.405751590.4352467440.6836964160.7377808843.3213725391.3107117950.826141513
182852.9763138382.1265804821.594725023-0.2693761280.6302348240.4981994330.8159333310.3750927620.665483877-0.1992361460.455221686-0.7244502730.574203634-0.173748811-0.4476468691.4282241850.272898383-0.3857246380.6660690251.2341274471.339323862-0.539351410.567461509
183235-0.1165389490.202925675-0.3346125630.6246481880.0870480530.2712151620.3755110570.273731680.058848872-0.4853377730.23457767-0.8987948460.4097810730.0968754510.213000476-0.561489077-0.783943328-0.369340261-0.482119240.258780716-0.0520129081.167211151.057529027
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10067 is not tested in classification assay
Integrated Annotations for CG10067 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
cytoskeleton organizationGO:0007010inferred from sequence or structural similarity
cytokinesis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
actin filamentGO:0005884inferred from sequence or structural similarity
actin filament
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
structural constituent of cytoskeletonGO:0005200inferred from sequence or structural similarity
glucuronosyltransferase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10067 in FlyBase
FLIGHTClick here to see CG10067 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10067 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10067
Entrez GeneEntrez Gene page for CG10067
UniprotUniprot page for CG10067

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)