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Gene Page - CG Number : CG10084
Gene Summary - CG10084:

CG10084: The gene second mitotic wave missing is referred to in FlyBase by the symbol Dmel\swm (CG10084, FBgn0002044). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleotide binding; zinc ion binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process: negative regulation of smoothened signaling pathway. 24 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic tergum; wing; wing vein; wing hair. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; Splicing factor PWI; Zinc finger, CCCH-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages.

Gene summary for CG10084 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10084:CG10084 is perturbed in following parameters in primary screen: Okt
CG10084 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10084.
Cell Count:
CG_NumberCategoryR1R2R3
CG10084Primary screen243560265
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10084:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812462.1475948013.5906270014.1999560491.052115334-1.081464744-1.470654979-0.78555212-2.474326471-0.5451639012.1126309982.3783812342.3256374881.9677574951.6062657163.568306352-0.5927217230.9194801572.5981344080.76255684-0.763127135-0.5021517050.5915026852.851791296
182404.2157324971.7800189560.6128575520.112773216-0.84321504-2.764489913-0.954159386-3.1176924740.8768467598.3029263774.1890063311.054367251.2766254270.6103953977.6230014640.4631965967.8290493349.0161557948.246888220.1094201120.3452920920.6926692852.156053852
183190-0.392719827-0.3062052870.126213558-0.644960019-0.990022747-0.917380783-0.877147316-1.225053981-0.983530990.792883311-0.463733128-0.022306503-0.115056818-0.73441993-0.041329233-1.021270639-0.546346338-0.328950751-0.204984185-1.008569630.7760987991.4638968210.88773132
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10084 is not tested in classification assay
Integrated Annotations for CG10084 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of mitotic cell cycleGO:0007346non-traceable author statement
negative regulation of smoothened signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634non-traceable author statement
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
zinc ion bindingGO:0008270inferred from electronic annotation with InterPro:IPR000571
nucleic acid binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10084 in FlyBase
FLIGHTClick here to see CG10084 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10084 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10084
Entrez GeneEntrez Gene page for CG10084
UniprotUniprot page for CG10084

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)