.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10107Gene Summary - CG10107:CG10107: The gene veloren is referred to in FlyBase by the symbol Dmel\velo (CG10107, FBgn0035713). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: SUMO-specific protease activity; cysteine-type peptidase activity. There is experimental evidence that it is involved in the biological process: negative regulation of cell death; axon guidance; dendritic spine morphogenesis; central nervous system projection neuron axonogenesis. 12 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Peptidase C48, SUMO/Sentrin/Ubl1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Gene summary for CG10107 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10107:CG10107 is perturbed in following parameters in primary screen: Tint3 Tint4 Tmph2 CG10107 is not tested in classification assay (fluid). CG10107 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tint4- Tmph1- Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10107.Cell Count:CG_NumberCategoryR1R2R3CG10107Primary screen284587476CG10107Secondary assay9201021889R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10107: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize1812660.0425507190.5842001120.5569263130.762760776-0.306452188-0.303129417-0.502331721-0.4982019782.5697917111.432272714.9882544791.8367518154.5454366653.05047312414.688702544.41730166116.440227148.84478938826.368354983.642393370.085925921-0.918146244-0.140215101182501.2302107820.5780420620.219166741-0.596716050.379789563-0.606354603-0.728922341-0.6016535940.4755227042.5705604831.653565061-0.0091855350.26410024-0.0359698271.6371926020.2278443061.4387522944.7529341521.5214245720.1760800040.0180622840.989076311.013181792183200-0.619128952-0.1729029580.542193449-0.490551580.115119835-0.160643370.118899289-0.1463030891.1574834553.2067031093.234136504-0.4674799080.4673747641.0725479311.0937342610.7837946471.8921624912.906130982.5658263961.2180478160.065111063-0.1614516240.560481616 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):Transferrin:CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3CG10107Slide1F0.1871.1131.0191.145CG10107Slide1O0.9981.1000.8961.005CG10107Slide1T0.3021.0230.5890.829F=Fdex; O=Surface TfR (Okt9); T=TfIntegrated Annotations for CG10107 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidenceproteolysisGO:0006508inferred by curator from GO:0008234 proteolysisGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidence-Gene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidencecysteine-type peptidase activityGO:0008234inferred from sequence or structural similarity with SGD_LOCUS:ULP2; SGD:S0001293 Other annotations DatabaseLinkFlyBaseClick here to see CG10107 in FlyBaseFLIGHTClick here to see CG10107 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10107 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10107Entrez GeneEntrez Gene page for CG10107UniprotUniprot page for CG10107 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10107Gene Summary - CG10107:CG10107: The gene veloren is referred to in FlyBase by the symbol Dmel\velo (CG10107, FBgn0035713). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: SUMO-specific protease activity; cysteine-type peptidase activity. There is experimental evidence that it is involved in the biological process: negative regulation of cell death; axon guidance; dendritic spine morphogenesis; central nervous system projection neuron axonogenesis. 12 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Peptidase C48, SUMO/Sentrin/Ubl1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. Gene summary for CG10107 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10107:CG10107 is perturbed in following parameters in primary screen: Tint3 Tint4 Tmph2 CG10107 is not tested in classification assay (fluid). CG10107 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tint4- Tmph1- Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10107.Cell Count:CG_NumberCategoryR1R2R3CG10107Primary screen284587476CG10107Secondary assay9201021889R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10107: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize1812660.0425507190.5842001120.5569263130.762760776-0.306452188-0.303129417-0.502331721-0.4982019782.5697917111.432272714.9882544791.8367518154.5454366653.05047312414.688702544.41730166116.440227148.84478938826.368354983.642393370.085925921-0.918146244-0.140215101182501.2302107820.5780420620.219166741-0.596716050.379789563-0.606354603-0.728922341-0.6016535940.4755227042.5705604831.653565061-0.0091855350.26410024-0.0359698271.6371926020.2278443061.4387522944.7529341521.5214245720.1760800040.0180622840.989076311.013181792183200-0.619128952-0.1729029580.542193449-0.490551580.115119835-0.160643370.118899289-0.1463030891.1574834553.2067031093.234136504-0.4674799080.4673747641.0725479311.0937342610.7837946471.8921624912.906130982.5658263961.2180478160.065111063-0.1614516240.560481616 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):Transferrin:CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3CG10107Slide1F0.1871.1131.0191.145CG10107Slide1O0.9981.1000.8961.005CG10107Slide1T0.3021.0230.5890.829F=Fdex; O=Surface TfR (Okt9); T=TfIntegrated Annotations for CG10107 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidenceproteolysisGO:0006508inferred by curator from GO:0008234 proteolysisGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidence-Gene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidencecysteine-type peptidase activityGO:0008234inferred from sequence or structural similarity with SGD_LOCUS:ULP2; SGD:S0001293 Other annotations DatabaseLinkFlyBaseClick here to see CG10107 in FlyBaseFLIGHTClick here to see CG10107 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10107 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10107Entrez GeneEntrez Gene page for CG10107UniprotUniprot page for CG10107
CG10107: The gene veloren is referred to in FlyBase by the symbol Dmel\velo (CG10107, FBgn0035713). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: SUMO-specific protease activity; cysteine-type peptidase activity. There is experimental evidence that it is involved in the biological process: negative regulation of cell death; axon guidance; dendritic spine morphogenesis; central nervous system projection neuron axonogenesis. 12 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Peptidase C48, SUMO/Sentrin/Ubl1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)