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Gene Page - CG Number : CG10107
Gene Summary - CG10107:

CG10107: The gene veloren is referred to in FlyBase by the symbol Dmel\velo (CG10107, FBgn0035713). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: SUMO-specific protease activity; cysteine-type peptidase activity. There is experimental evidence that it is involved in the biological process: negative regulation of cell death; axon guidance; dendritic spine morphogenesis; central nervous system projection neuron axonogenesis. 12 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Peptidase C48, SUMO/Sentrin/Ubl1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG10107 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10107:CG10107 is perturbed in following parameters in primary screen: Tint3 Tint4 Tmph2
CG10107 is not tested in classification assay (fluid).
CG10107 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tint4- Tmph1-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10107.
Cell Count:
CG_NumberCategoryR1R2R3
CG10107Primary screen284587476
CG10107Secondary assay9201021889
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10107:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812660.0425507190.5842001120.5569263130.762760776-0.306452188-0.303129417-0.502331721-0.4982019782.5697917111.432272714.9882544791.8367518154.5454366653.05047312414.688702544.41730166116.440227148.84478938826.368354983.642393370.085925921-0.918146244-0.140215101
182501.2302107820.5780420620.219166741-0.596716050.379789563-0.606354603-0.728922341-0.6016535940.4755227042.5705604831.653565061-0.0091855350.26410024-0.0359698271.6371926020.2278443061.4387522944.7529341521.5214245720.1760800040.0180622840.989076311.013181792
183200-0.619128952-0.1729029580.542193449-0.490551580.115119835-0.160643370.118899289-0.1463030891.1574834553.2067031093.234136504-0.4674799080.4673747641.0725479311.0937342610.7837946471.8921624912.906130982.5658263961.2180478160.065111063-0.1614516240.560481616
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10107Slide1F0.1871.1131.0191.145
CG10107Slide1O0.9981.1000.8961.005
CG10107Slide1T0.3021.0230.5890.829
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10107 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
proteolysisGO:0006508inferred by curator from GO:0008234
proteolysis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
cysteine-type peptidase activityGO:0008234inferred from sequence or structural similarity with SGD_LOCUS:ULP2; SGD:S0001293
Other annotations
DatabaseLink
FlyBaseClick here to see CG10107 in FlyBase
FLIGHTClick here to see CG10107 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10107 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10107
Entrez GeneEntrez Gene page for CG10107
UniprotUniprot page for CG10107

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)