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Gene Page - CG Number : CG10116
Gene Summary - CG10116:

CG10116: This gene is referred to in FlyBase by the symbol Dmel\CG10116 (FBgn0036367). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: lipoprotein lipase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: lipid metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Lipase; Lipase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.

Gene summary for CG10116 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10116:CG10116 is perturbed in following parameters in primary screen: Okt Tint2 Tmph2
CG10116 is not tested in classification assay (fluid).
CG10116 is perturbed in following parameters in classification assay (transferrin): CellSize+(tfr) Fint1+ Fmph2+ Fmph3+ Fnum+ NuCellD-(tfr) NuSize-(tfr) Rto1-(tfr) Rto2-(tfr) Tint4- Tmph3+ Tnum+
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10116.
Cell Count:
CG_NumberCategoryR1R2R3
CG10116Primary screen337857446
CG10116Secondary assay790539570
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10116:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812681.505130082-0.350610192-0.6441658550.325187072-0.076765179-0.218864993-1.107490683-0.5900088120.5473060922.4664172212.742773292-0.229495980.5975752090.7771992844.242546025-0.1180920882.499734423.3824481682.1101576360.4898625261.8156444443.9407570310.593448103
18248-0.165359613-0.727568669-0.777618691-0.3833488180.5698668240.7156722710.1226907670.7133645011.9894651874.7917768333.3650313470.4762366160.79654310.7156246843.9162401820.4358825196.047023225.2421023383.5750255191.6417036820.929096344-0.284169487-0.122202622
1831981.068976911-0.592571141-0.3852092910.066297623-0.479907697-1.09614966-0.759042206-1.019610636-0.4621016371.3236187840.5272847710.970775717-0.0070653140.4346426394.405309263-0.3732134360.188294351-0.3689117420.129209558-0.3575620050.0257798721.005279655-0.732063894
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10116Slide10F0.0381.2811.1781.110
CG10116Slide10O0.1331.2541.1841.708
CG10116Slide10T0.2091.5231.0471.210
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10116 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
lipid metabolic processGO:0006629inferred from electronic annotation with InterPro:IPR000734
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
lipoprotein lipase activityGO:0004465inferred from sequence or structural similarity with UniProtKB:P11153
Other annotations
DatabaseLink
FlyBaseClick here to see CG10116 in FlyBase
FLIGHTClick here to see CG10116 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10116 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10116
Entrez GeneEntrez Gene page for CG10116
UniprotUniprot page for CG10116

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)