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Gene Page - CG Number : CG10117
Gene Summary - CG10117:

CG10117: The gene tout-velu is referred to in FlyBase by the symbol Dmel\ttv (CG10117, FBgn0020245). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence for 12 unique biological process terms, many of which group under: biological regulation; localization; heparan sulfate proteoglycan biosynthetic process; organonitrogen compound metabolic process; cellular component organization or biogenesis; response to stimulus; gene expression; organic substance biosynthetic process; cellular biosynthetic process; cellular macromolecule biosynthetic process. 68 alleles are reported. The phenotypes of these alleles are annotated with: wing disc; trichogen cell; cuticle; macrochaeta; bouton; germline cell; synapse; denticle belt. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: EXTL2, alpha-1,4-N-acetylhexosaminyltransferase; Exostosin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10117 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10117:CG10117 is not perturbed in primary screen.
CG10117 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10117.
Cell Count:
CG_NumberCategoryR1R2R3
CG10117Primary screen252993454
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10117:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812690.670786264-0.2263579860.2552098322.983592663-0.679369721-1.022868535-0.514757584-1.287427069-1.468874461-0.1482781230.9280040231.8996678430.5838621630.4932589630.715084049-1.289293252-0.433056154-0.186844906-0.559654143-1.3788615580.5665835060.785985076-0.004656507
182472.2088800531.8182777291.3443554272.4007964991.11378261.535919321.7216047571.482059371.6875505391.5013322441.2866990450.2263804350.7627227320.2373281144.2538725740.817075331.3225373851.2846676281.3105009331.2410864993.131161273-0.3400850180.090075811
1831970.0716300750.359934696-0.053380188-1.2043132010.6985063270.4039276640.3488990660.4030205750.704407472.0436205642.409829966-0.6605555371.637491022.155205957-0.377687593-0.2637270852.6380530631.5874491431.0899010610.8441035780.518503663-0.573128476-0.44640598
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10117 is not tested in classification assay
Integrated Annotations for CG10117 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
germ cell migrationGO:0008354inferred from mutant phenotype
regulation of smoothened signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021non-traceable author statement
Golgi apparatus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
acetylglucosaminyltransferase activityGO:0008375inferred from sequence or structural similarity with EMBL:AF089748
acetylglucosaminyltransferase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10117 in FlyBase
FLIGHTClick here to see CG10117 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10117 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10117
Entrez GeneEntrez Gene page for CG10117
UniprotUniprot page for CG10117

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)