.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10119Gene Summary - CG10119:CG10119: The gene Lamin C is referred to in FlyBase by the symbol Dmel\LamC (CG10119, FBgn0010397). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: structural molecule activity. There is experimental evidence that it is involved in the biological process: muscle tissue morphogenesis; nuclear pore distribution; chromatin silencing; regulation of actin filament polymerization. 43 alleles are reported. The phenotypes of these alleles are annotated with: metathoracic tarsal segment; metathoracic femur; embryonic/larval salivary gland; metathoracic metatarsus; mesothoracic tergum; imaginal disc; metathoracic tibia; ventral thoracic disc; nucleus; embryonic/larval somatic muscle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Filament; Intermediate filament protein; Lamin Tail Domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages. Gene summary for CG10119 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10119:CG10119 is not perturbed in primary screen. CG10119 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10119.Cell Count:CG_NumberCategoryR1R2R3CG10119Primary screen277876471R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10119: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize1812710.372056558-0.386897828-0.156500883-0.7415493-0.454381513-0.623057015-1.37141676-0.7648506080.1988991123.5693794142.277163329-0.4114455440.6212899940.618478030.860112649-0.5820326511.5828625513.0398783142.127455350.1125285630.222116839-0.079819981-0.53606596818215-0.174485522-0.125278290.089735968-0.7773687390.5950967530.8527894480.509362040.7912849610.2683384270.0358269660.32288771-0.0517099680.361290977-0.0139939331.5153743150.7846244360.200177418-0.3319300740.6237518270.3407519720.5260633520.8828176010.222652674183165-0.589449351-0.5136338230.121523594-0.3989375950.1063585950.040219938-0.2190230110.057692083-0.2096852772.358297854-0.419020167-0.735175578-0.537791218-0.8493482071.1706190510.767934117-0.7499645-0.585279598-0.499849744-0.212478076-0.366112355-0.0887582881.098413986 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10119 is not tested in classification assayIntegrated Annotations for CG10119 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencemitotic nuclear envelope reassemblyGO:0007084inferred from sequence or structural similarity with EMBL:D50080; protein_id:BAA08784 nuclear pore distributionGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencelamin filamentGO:0005638non-traceable author statement lamin filamentGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidencestructural molecule activityGO:0005198inferred from electronic annotation with InterPro:IPR001664 Other annotations DatabaseLinkFlyBaseClick here to see CG10119 in FlyBaseFLIGHTClick here to see CG10119 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10119 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10119Entrez GeneEntrez Gene page for CG10119UniprotUniprot page for CG10119 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10119Gene Summary - CG10119:CG10119: The gene Lamin C is referred to in FlyBase by the symbol Dmel\LamC (CG10119, FBgn0010397). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: structural molecule activity. There is experimental evidence that it is involved in the biological process: muscle tissue morphogenesis; nuclear pore distribution; chromatin silencing; regulation of actin filament polymerization. 43 alleles are reported. The phenotypes of these alleles are annotated with: metathoracic tarsal segment; metathoracic femur; embryonic/larval salivary gland; metathoracic metatarsus; mesothoracic tergum; imaginal disc; metathoracic tibia; ventral thoracic disc; nucleus; embryonic/larval somatic muscle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Filament; Intermediate filament protein; Lamin Tail Domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages. Gene summary for CG10119 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10119:CG10119 is not perturbed in primary screen. CG10119 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10119.Cell Count:CG_NumberCategoryR1R2R3CG10119Primary screen277876471R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10119: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize1812710.372056558-0.386897828-0.156500883-0.7415493-0.454381513-0.623057015-1.37141676-0.7648506080.1988991123.5693794142.277163329-0.4114455440.6212899940.618478030.860112649-0.5820326511.5828625513.0398783142.127455350.1125285630.222116839-0.079819981-0.53606596818215-0.174485522-0.125278290.089735968-0.7773687390.5950967530.8527894480.509362040.7912849610.2683384270.0358269660.32288771-0.0517099680.361290977-0.0139939331.5153743150.7846244360.200177418-0.3319300740.6237518270.3407519720.5260633520.8828176010.222652674183165-0.589449351-0.5136338230.121523594-0.3989375950.1063585950.040219938-0.2190230110.057692083-0.2096852772.358297854-0.419020167-0.735175578-0.537791218-0.8493482071.1706190510.767934117-0.7499645-0.585279598-0.499849744-0.212478076-0.366112355-0.0887582881.098413986 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10119 is not tested in classification assayIntegrated Annotations for CG10119 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencemitotic nuclear envelope reassemblyGO:0007084inferred from sequence or structural similarity with EMBL:D50080; protein_id:BAA08784 nuclear pore distributionGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencelamin filamentGO:0005638non-traceable author statement lamin filamentGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidencestructural molecule activityGO:0005198inferred from electronic annotation with InterPro:IPR001664 Other annotations DatabaseLinkFlyBaseClick here to see CG10119 in FlyBaseFLIGHTClick here to see CG10119 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10119 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10119Entrez GeneEntrez Gene page for CG10119UniprotUniprot page for CG10119
CG10119: The gene Lamin C is referred to in FlyBase by the symbol Dmel\LamC (CG10119, FBgn0010397). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: structural molecule activity. There is experimental evidence that it is involved in the biological process: muscle tissue morphogenesis; nuclear pore distribution; chromatin silencing; regulation of actin filament polymerization. 43 alleles are reported. The phenotypes of these alleles are annotated with: metathoracic tarsal segment; metathoracic femur; embryonic/larval salivary gland; metathoracic metatarsus; mesothoracic tergum; imaginal disc; metathoracic tibia; ventral thoracic disc; nucleus; embryonic/larval somatic muscle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Filament; Intermediate filament protein; Lamin Tail Domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)