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Gene Page - CG Number : CG10122
Gene Summary - CG10122:

CG10122: The gene RNA polymerase I subunit is referred to in FlyBase by the symbol Dmel\RpI1 (CG10122, FBgn0019938). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: DNA-directed RNA polymerase activity. Based on sequence similarity, it is predicted to be involved in the biological process: transcription from RNA polymerase I promoter. 5 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA-directed RNA pol I, largest subunit; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; RNA polymerase, N-terminal; RNA polymerase, alpha subunit. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.

Gene summary for CG10122 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10122:CG10122 is not perturbed in primary screen.
CG10122 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10122.
Cell Count:
CG_NumberCategoryR1R2R3
CG10122Primary screen239969369
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10122:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
181273-0.165012857-0.704490947-0.3389542920.108996768-0.763733363-1.559926518-1.496684008-1.986571402-1.6909385070.0851908220.059289989-0.72878750.2388011910.3254902650.514973487-1.2669411821.212472107-0.232030629-0.350655422-1.617600161.78865673-0.2460371690.287310025
182130.214602315-0.221016919-0.1944035910.0267859430.5330499632.3720284252.999033841.8506680343.0685216750.19083271-0.5021638880.2917795230.8805897110.6057994740.039291270.5304643031.0973407211.4407373211.5812639633.643739480.8177896241.3259702733.247256182
183163-0.562867711-0.917355649-0.715380117-0.676462387-0.49608049-0.837950441-0.546558758-1.0562899210.4156465441.8949334621.1141725740.011204496-0.330976607-0.0282134331.0440521440.2958997520.9607211442.4750975331.7096343930.3805535950.5992756790.1860652090.045199028
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10122 is not tested in classification assay
Integrated Annotations for CG10122 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transcription from RNA polymerase I promoterGO:0006360inferred from sequence or structural similarity with UniProtKB:O54889
transcription from RNA polymerase I promoter
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
DNA-directed RNA polymerase I complexGO:0005736inferred from sequence or structural similarity with UniProtKB:O54889
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
DNA-directed RNA polymerase activityGO:0003899non-traceable author statement
DNA-directed RNA polymerase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10122 in FlyBase
FLIGHTClick here to see CG10122 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10122 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10122
Entrez GeneEntrez Gene page for CG10122
UniprotUniprot page for CG10122

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)