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Gene Page - CG Number : CG10124
Gene Summary - CG10124:

CG10124: The gene eIF4E-4 is referred to in FlyBase by the symbol Dmel\eIF4E-4 (CG10124, FBgn0035709). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: translation initiation factor activity; protein binding; eukaryotic initiation factor 4G binding; RNA 7-methylguanosine cap binding. There is experimental evidence that it is involved in the biological process: translational initiation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Eukaryotic translation initiation factor 4E (eIF-4E), conserved site; Translation Initiation factor eIF- 4e; Translation Initiation factor eIF- 4e-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected. Peak expression observed during late pupal stages, in adult male stages.

Gene summary for CG10124 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10124:CG10124 is not perturbed in primary screen.
CG10124 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10124.
Cell Count:
CG_NumberCategoryR1R2R3
CG10124Primary screen112919482
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10124:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812740.645402627-0.899447031-0.3495880520.747949016-2.419362765-3.463190602-2.790216241-3.9668403-3.488973417-0.6185943960.092122217-0.1301918772.5443721380.723455552-0.160601918-1.407037597-0.638926327-0.2616735020.679820434-3.5116962390.803769376-0.760743716-1.045498547
18212-0.602156303-0.663820999-0.653548183-0.288480730.7624740851.1072761940.971018851.2561301951.4543498160.3965263191.118699238-0.475507772-1.124569372-0.6010739630.1433493491.038792961.057191867-0.2499088240.7011284971.393840852.2438367930.1391040490.8744205
183162-0.32475842-0.2055382780.194429786-0.2425026380.5483212390.254190417-0.0277486190.4196895080.391955114-0.499711299-0.594632271-0.181249305-1.610144722-1.2915201730.2253321760.1539255421.727126523-0.15953670.087721980.417533447-0.779886716-0.323997417-0.313312321
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10124 is not tested in classification assay
Integrated Annotations for CG10124 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
translational initiationGO:0006413inferred from sequence or structural similarity with UniProtKB:O77210
translational initiation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
eukaryotic translation initiation factor 4F complexGO:0016281inferred from sequence or structural similarity
eukaryotic translation initiation factor 4F complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
RNA cap bindingGO:0000339inferred from sequence or structural similarity
translation initiation factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10124 in FlyBase
FLIGHTClick here to see CG10124 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10124 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10124
Entrez GeneEntrez Gene page for CG10124
UniprotUniprot page for CG10124

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)