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Gene Page - CG Number : CG10129
Gene Summary - CG10129:

CG10129: The gene nudel is referred to in FlyBase by the symbol Dmel\ndl (CG10129, FBgn0002926). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: serine-type peptidase activity; peptidase activity; serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: eggshell chorion assembly; protein processing; dorsal/ventral axis specification; egg activation. 30 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; vitelline membrane; egg; embryo. It has one annotated transcript and one annotated polypeptide. Protein features are: Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, nudel; Peptidase cysteine/serine, trypsin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed in adult female stages.

Gene summary for CG10129 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10129:CG10129 is not perturbed in primary screen.
CG10129 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10129.
Cell Count:
CG_NumberCategoryR1R2R3
CG10129Primary screen418905589
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10129:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812781.5247212560.946591046-0.40241484-0.1802197590.5281196450.7553166411.0325365780.7909194681.1702453891.125216612.650555826-0.5100476360.7731285240.925591141-0.140845508-0.5692800772.1578858651.3446564571.5303776251.365296543-0.14805385-0.065947695-0.641573149
18281.4783075431.7039956860.6126903322.9040704840.9024267520.9086628450.8246699460.9740879671.042656425-0.9042941340.272806771-0.2984823530.445911287-0.1238320821.4350734321.502098257-1.062596071-0.58231888-0.5864854121.0850067822.04145172-0.284463994-0.066060706
183158-0.180748704-0.472654321-0.207911513-0.5154131651.1105017361.0959535840.9253028290.9373787571.3598726110.9783252180.7647208320.1306077090.8227779711.048638319-0.089708433-0.0693560982.3898894170.8039379481.2543782261.2626804980.221732222-0.1184501930.118911238
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10129 is not tested in classification assay
Integrated Annotations for CG10129 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
dorsal/ventral axis specificationGO:0009950inferred from mutant phenotype
Toll signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
extracellular regionGO:0005576non-traceable author statement
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
serine-type peptidase activityGO:0008236traceable author statement
serine-type peptidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10129 in FlyBase
FLIGHTClick here to see CG10129 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10129 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10129
Entrez GeneEntrez Gene page for CG10129
UniprotUniprot page for CG10129

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)