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Gene Page - CG Number : CG10160
Gene Summary - CG10160:

CG10160: The gene Ecdysone-inducible gene L3 is referred to in FlyBase by the symbol Dmel\ImpL3 (CG10160, FBgn0001258). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: L-lactate dehydrogenase activity. It is reported to be involved in the biological process: glycolysis. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: L-lactate dehydrogenase; L-lactate dehydrogenase, active site; L-lactate/malate dehydrogenase; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; Lactate/malate dehydrogenase, C-terminal; Lactate/malate dehydrogenase, N-terminal; NAD(P)-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period.

Gene summary for CG10160 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10160:CG10160 is not perturbed in primary screen.
CG10160 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10160.
Cell Count:
CG_NumberCategoryR1R2R3
CG10160Primary screen433541489
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10160:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1812963.2961627171.44939561.7748413523.017694655-0.217132259-2.1877826660.542686268-3.017569413-2.287658809-0.616236726-1.2764105-0.623002597-0.953126668-0.059495041-0.4895331241.316635545-2.20143154-1.0761528310.024179917-2.4119069061.04424285-0.1885491870.190858129
182201.4145748850.9959246791.8384897390.589693798-0.093308419-0.376775096-0.220114652-1.076383128-1.3392782350.836713746-1.0358278570.073228434-0.629439574-1.3018752731.7978100480.522955874-1.531612331-0.554056568-1.332864146-1.2151965260.889362635-0.646314628-0.462491651
183170-0.129689594-0.702008807-0.195255613-0.3365627420.1398625370.3824533260.0214854090.3364937110.470471590.048191187-0.279030181-0.032237852-0.241606347-0.4650144970.2783403920.3963268510.751073806-0.2186428210.4109272410.572597112-0.83402102-0.576711385-0.446172726
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10160 is not tested in classification assay
Integrated Annotations for CG10160 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
glycolysisGO:0006096non-traceable author statement
oxidation-reduction process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from electronic annotation with InterPro:IPR011304
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
L-lactate dehydrogenase activityGO:0004459traceable author statement
L-lactate dehydrogenase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10160 in FlyBase
FLIGHTClick here to see CG10160 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10160 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10160
Entrez GeneEntrez Gene page for CG10160
UniprotUniprot page for CG10160

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)