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Gene Page - CG Number : CG10173
Gene Summary - CG10173:

CG10173: The gene Bestrophin 2 is referred to in FlyBase by the symbol Dmel\Best2 (CG10173, FBgn0035696). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: anion channel activity. Based on sequence similarity, it is predicted to be involved in the biological process: anion transport. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Bestrophin; Bestrophin/UPF0187. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.

Gene summary for CG10173 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10173:CG10173 is not perturbed in primary screen.
CG10173 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10173.
Cell Count:
CG_NumberCategoryR1R2R3
CG10173Primary screen278803676
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10173:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19141.930209746-0.2173422280.63723862-0.029770312-0.848901052-1.103954146-1.029880893-1.502675429-1.527979540.445917735-0.9874146182.55701761-0.152625257-0.5656460270.4044016430.025548801-1.12900892-0.6701390151.232055553-1.1571203391.7195727090.554610615-0.179735651
1921621.4254064571.0828384290.9882536641.0185910880.3279611610.7114370960.8667734730.7194418891.0406915830.8983860530.778319815-0.2483267730.304897580.3417043050.4333107190.4352271352.1422408850.3863880281.0650402851.1313504362.154449083-0.159561683-0.530573745
193132-0.069359167-0.2912334161.031998092-0.2128310972.0870018791.791729612.706592012.3776218421.6649878111.1022129340.513490273-0.0224469310.895109770.4827424681.6088480550.8984350190.6076072970.0253415710.8322157941.8749025651.3638193292.8680149992.364006956
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10173 is not tested in classification assay
Integrated Annotations for CG10173 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
anion transportGO:0006820inferred from sequence or structural similarity with Best1
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from sequence or structural similarity with Best1
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
anion channel activityGO:0005253inferred from sequence or structural similarity with Best1
Other annotations
DatabaseLink
FlyBaseClick here to see CG10173 in FlyBase
FLIGHTClick here to see CG10173 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10173 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10173
Entrez GeneEntrez Gene page for CG10173
UniprotUniprot page for CG10173

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)