Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG10197
Gene Summary - CG10197:

CG10197: The gene knot is referred to in FlyBase by the symbol Dmel\kn (CG10197, FBgn0001319). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: sequence-specific DNA binding transcription factor activity. There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; system development; multicellular organismal development; embryonic pattern specification; cellular process; post-embryonic organ morphogenesis; immune response; response to other organism; embryonic development via the syncytial blastoderm; muscle cell differentiation; segment specification; cellular component organization or biogenesis; somatic muscle development. 28 alleles are reported. The phenotypes of these alleles are annotated with 46 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; adult segment; organ system subdivision; larval abdominal segment; thoracic segment; cephalopharyngeal skeleton; peripheral nervous system; pharyngeal sclerite; hypodermal muscle of larval abdominal 2. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Cell surface receptor IPT/TIG; Helix-loop-helix domain; Immunoglobulin E-set; Immunoglobulin-like fold; Transcription factor COE; Transcription factor COE, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed at stages throughout embryogenesis.

Gene summary for CG10197 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10197:CG10197 is not perturbed in primary screen.
CG10197 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10197.
Cell Count:
CG_NumberCategoryR1R2R3
CG10197Primary screen475882621
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10197:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191210.6831016720.334226579-0.1103112611.0102800090.5879316910.9775834810.7818033910.9829273721.3621046331.9917623831.448152945-0.5701017421.2984749550.76659233-0.0797469440.6533834391.4239344090.7750212891.2740295841.3903377122.4868335170.7810274990.371656842
192175-0.417227265-0.283898635-0.401318275-0.8031313140.5921796760.9801443260.7275392861.1206276971.8809101652.1351442311.967447001-0.1095767790.6487320481.05622269-0.5233400190.0226912371.9212639992.6138986881.661313451.7711313780.783917301-0.112793131-0.356630572
193145-0.175230769-0.448120016-0.4759834480.8199650310.4978021540.8940159480.5150742350.9037448291.1569239030.1865297110.2430928620.2056345570.738663705-0.0260827010.037897460.374970471.0292556720.375463461.2445246331.263069115-0.342148340.7737158650.010333161
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10197 is not tested in classification assay
Integrated Annotations for CG10197 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
embryonic development via the syncytial blastodermGO:0001700inferred from mutant phenotype
head segmentation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634non-traceable author statement
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700non-traceable author statement
DNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10197 in FlyBase
FLIGHTClick here to see CG10197 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10197 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10197
Entrez GeneEntrez Gene page for CG10197
UniprotUniprot page for CG10197

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)