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Gene Page - CG Number : CG10198
Gene Summary - CG10198:

CG10198: The gene Nucleoporin 98-96 is referred to in FlyBase by the symbol Dmel\Nup98-96 (CG10198, FBgn0039120). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: germ-line stem cell maintenance; SMAD protein import into nucleus; phagocytosis, engulfment. 15 alleles are reported. The phenotypes of these alleles are annotated with: female fusome; nurse cell spectrosome; male germline cell. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Nuclear protein 96; Peptidase S59, nucleoporin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10198 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10198:CG10198 is perturbed in following parameters in primary screen: Okt Tint1 Tint2 Tint3 Tint4 Tmph1 Tmph2 Tmph3
CG10198 is not tested in classification assay (fluid).
CG10198 is perturbed in following parameters in classification assay (transferrin): Fint1+ Rto2-(tfr) Rto3-(tfr) Tint1- Tint2- Tint3- Tint4-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10198.
Cell Count:
CG_NumberCategoryR1R2R3
CG10198Primary screen521879203
CG10198Secondary assay759455645
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10198:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191221.256143825-0.302191996-0.083405845-0.7826333440.789064971.2039790170.6998165151.0726946312.235102674.485348014.513593862-0.2400378061.3821875261.2757637037.5758878031.0012548366.7876414454.8020287843.9179487082.407705152-0.3274708650.387083507-0.335856301
1921740.5569699781.4298747561.792715114-0.6689883920.7000705770.1150914910.5082113870.2346964272.0218494715.8034571384.4982143331.2735122071.7735381851.3706280053.9396121650.709697995.0934006476.2787987914.690125811.3622437383.362362096-0.430143970.197989282
193144-1.2953179892.0585616290.579826645-0.201175322-0.958275156-0.77137927-1.15983819-1.572372737-0.7946742521.3164584722.112786307-1.044579710.1087857030.6619307076.473321171-0.2992137430.4141156563.3974646460.772889007-0.427964235-0.2892669220.161378978-0.564981493
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10198Slide1F0.0881.0741.1171.051
CG10198Slide1O0.5471.1010.9030.805
CG10198Slide1T0.7131.1790.9360.681
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10198 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
phagocytosis, engulfmentGO:0006911inferred from mutant phenotype
SMAD protein import into nucleus
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nuclear poreGO:0005643inferred from sequence or structural similarity with EMBL:AF071076; protein_id:AAD22395.1 AND inferred from sequence or structural similarity with UniProtKB:P49793
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG10198 in FlyBase
FLIGHTClick here to see CG10198 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10198 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10198
Entrez GeneEntrez Gene page for CG10198
UniprotUniprot page for CG10198

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)