Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG10215
Gene Summary - CG10215:

CG10215: The gene Ercc1 is referred to in FlyBase by the symbol Dmel\Ercc1 (CG10215, FBgn0028434). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; protein heterodimerization activity. There is experimental evidence that it is involved in the biological process: neuron projection morphogenesis; reciprocal meiotic recombination; nucleotide-excision repair. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA repair protein rad10; Restriction endonuclease type II--like; RuvA domain 2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10215 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10215:CG10215 is not perturbed in primary screen.
CG10215 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10215.
Cell Count:
CG_NumberCategoryR1R2R3
CG10215Primary screen557913542
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10215:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19135-0.592847674-0.4744915980.0595618731.1213754070.384630894-0.2375137490.61909246-0.847656930.3577560580.6002482080.7414355320.3921669940.9725877061.4281494230.7325707830.8266399410.4031487590.6114515630.8520154080.4332824063.1675596761.138509996-0.171739473
1921913.7950943451.1050522410.0873004160.9680137120.1996539731.2923466041.4845791311.2986873792.7068630713.172785066-0.678686731.70090942.0665584910.8551050930.945662615-0.0236101252.0871396192.9500794861.5903620692.046670189-0.4166153683.5539847865.10700277
193101-0.598505798-0.40685792-0.333517501-1.0111666180.9279064841.3697679360.3402711090.698220121.341265389-0.03669989-0.0111085460.116971951.1008557550.2840464540.369499397-0.0384313451.6358105971.2847879761.2275753491.526997809-0.007465260.06155912-0.14353495
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10215 is not tested in classification assay
Integrated Annotations for CG10215 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
reciprocal meiotic recombinationGO:0007131inferred from mutant phenotype
nucleotide-excision repair
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
protein complexGO:0043234inferred from direct assay
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
single-stranded DNA specific endodeoxyribonuclease activityGO:0000014inferred from sequence or structural similarity with UniProtKB:P07903
protein binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10215 in FlyBase
FLIGHTClick here to see CG10215 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10215 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10215
Entrez GeneEntrez Gene page for CG10215
UniprotUniprot page for CG10215

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)