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Gene Page - CG Number : CG10221
Gene Summary - CG10221:

CG10221: This gene is referred to in FlyBase by the symbol Dmel\Hrd3 (CG10221, FBgn0028475). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Sel1-like; Tetratricopeptide-like helical. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG10221 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10221:CG10221 is perturbed in following parameters in primary screen: CellSize Fint1
CG10221 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fclc- LP_Fint1+ LP_Fmph1- LP_Fnum- NuFluct+(fld) Okt+(fld) SP_Fclc-
CG10221 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10221.
Cell Count:
CG_NumberCategoryR1R2R3
CG10221Primary screen52552353
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10221:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19139-0.066499894-0.443373509-0.704893453-0.3675096520.8292875881.3264510961.2529375551.3734431991.367688316-1.015894687-0.36087465-0.194708936-0.951989194-1.282750104-0.060121051.518016414-2.151890489-0.546667015-1.8452048391.4876729984.0183569290.9122681220.69494464
1921874.2887756820.439178103-0.070563399-0.142453127-0.395962116-0.215869314-0.732466925-0.839114479-1.056253265-0.8945798890.0619103672.121805376-0.018213605-1.045563444-0.594481456-0.336989829-2.176196993-2.028553563-2.650025286-0.7114406373.7122473072.2572757592.975423677
193973.3632919737.5475638838.3174822575.2048965353.3156128924.4890759452.270643479.340543949-0.61811765-1.450901403-2.8545420640.940259755-0.3341775461.000578933-0.156974421-2.741540353-3.744183666-3.418617093-3.376899265-1.0932275761.7185983741.0478990550.707856356
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10221Slide19C0.2071.4901.6921.169
CG10221Slide19O0.0243.2372.1382.191
CG10221Slide19P0.6581.0811.1391.226
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10221 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
-
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
plasma membraneGO:0005886inferred from sequence or structural similarity with UniProtKB:Q9Z2G6
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
bindingGO:0005488inferred from electronic annotation with InterPro:IPR011990
Other annotations
DatabaseLink
FlyBaseClick here to see CG10221 in FlyBase
FLIGHTClick here to see CG10221 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10221 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10221
Entrez GeneEntrez Gene page for CG10221
UniprotUniprot page for CG10221

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)