.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10229Gene Summary - CG10229:CG10229: The gene Katanin 60 is referred to in FlyBase by the symbol Dmel\Kat60 (CG10229, FBgn0040208). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; microtubule-severing ATPase activity. There is experimental evidence that it is involved in the biological process: chaeta development; wing disc development; plus-end specific microtubule depolymerization; negative regulation of cell migration; microtubule depolymerization; cytoplasmic microtubule organization; mitotic anaphase A; mitotic sister chromatid segregation; microtubule severing. 11 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body; Kenyon cell; mushroom body alpha-lobe. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; Vps4 oligomerisation, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Gene summary for CG10229 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10229:CG10229 is not perturbed in primary screen. CG10229 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10229.Cell Count:CG_NumberCategoryR1R2R3CG10229Primary screen495788584R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10229: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize19146-0.27999286-0.274700678-0.468372876-0.2767374830.7050054141.1475031751.2532722631.2018222121.492752977-0.4064091481.018274635-0.5160714340.1128428740.564404313-0.3409672260.634578884-0.4891764090.162070854-0.6393080571.5845698390.260867985-0.150157340.468131673192210-0.268808297-0.27236818-0.469895985-0.4992563320.3107391130.7237736610.5150121770.7271769450.975857763-1.358923547-0.1659030792.3096654960.7616747450.6162087674.4504262850.048657554-0.727591858-0.505721793-0.8260819750.678099382.3049207991.9022357461.840835227193120-0.0808443040.5432755090.7416759282.6571543711.5098392512.6500375962.3143625272.2865294511.5027882081.4045100220.9479097340.0820131890.6909441030.7004504421.2960295210.1359546032.6990370060.3780078321.1882775381.9309630870.346654203-0.563105355-0.329800586 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10229 is not tested in classification assayIntegrated Annotations for CG10229 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencemicrotubule severingGO:0051013non-traceable author statement microtubule severingGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencekatanin complexGO:0008352non-traceable author statement katanin complexGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceprotein bindingGO:0005515inferred from physical interaction with Myo10A microtubule binding Other annotations DatabaseLinkFlyBaseClick here to see CG10229 in FlyBaseFLIGHTClick here to see CG10229 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10229 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10229Entrez GeneEntrez Gene page for CG10229UniprotUniprot page for CG10229 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10229Gene Summary - CG10229:CG10229: The gene Katanin 60 is referred to in FlyBase by the symbol Dmel\Kat60 (CG10229, FBgn0040208). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; microtubule-severing ATPase activity. There is experimental evidence that it is involved in the biological process: chaeta development; wing disc development; plus-end specific microtubule depolymerization; negative regulation of cell migration; microtubule depolymerization; cytoplasmic microtubule organization; mitotic anaphase A; mitotic sister chromatid segregation; microtubule severing. 11 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body; Kenyon cell; mushroom body alpha-lobe. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; Vps4 oligomerisation, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Gene summary for CG10229 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10229:CG10229 is not perturbed in primary screen. CG10229 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10229.Cell Count:CG_NumberCategoryR1R2R3CG10229Primary screen495788584R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10229: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize19146-0.27999286-0.274700678-0.468372876-0.2767374830.7050054141.1475031751.2532722631.2018222121.492752977-0.4064091481.018274635-0.5160714340.1128428740.564404313-0.3409672260.634578884-0.4891764090.162070854-0.6393080571.5845698390.260867985-0.150157340.468131673192210-0.268808297-0.27236818-0.469895985-0.4992563320.3107391130.7237736610.5150121770.7271769450.975857763-1.358923547-0.1659030792.3096654960.7616747450.6162087674.4504262850.048657554-0.727591858-0.505721793-0.8260819750.678099382.3049207991.9022357461.840835227193120-0.0808443040.5432755090.7416759282.6571543711.5098392512.6500375962.3143625272.2865294511.5027882081.4045100220.9479097340.0820131890.6909441030.7004504421.2960295210.1359546032.6990370060.3780078321.1882775381.9309630870.346654203-0.563105355-0.329800586 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10229 is not tested in classification assayIntegrated Annotations for CG10229 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencemicrotubule severingGO:0051013non-traceable author statement microtubule severingGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencekatanin complexGO:0008352non-traceable author statement katanin complexGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceprotein bindingGO:0005515inferred from physical interaction with Myo10A microtubule binding Other annotations DatabaseLinkFlyBaseClick here to see CG10229 in FlyBaseFLIGHTClick here to see CG10229 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10229 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10229Entrez GeneEntrez Gene page for CG10229UniprotUniprot page for CG10229
CG10229: The gene Katanin 60 is referred to in FlyBase by the symbol Dmel\Kat60 (CG10229, FBgn0040208). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; microtubule-severing ATPase activity. There is experimental evidence that it is involved in the biological process: chaeta development; wing disc development; plus-end specific microtubule depolymerization; negative regulation of cell migration; microtubule depolymerization; cytoplasmic microtubule organization; mitotic anaphase A; mitotic sister chromatid segregation; microtubule severing. 11 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body; Kenyon cell; mushroom body alpha-lobe. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; Vps4 oligomerisation, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)