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Gene Page - CG Number : CG10236
Gene Summary - CG10236:

CG10236: The gene Laminin A is referred to in FlyBase by the symbol Dmel\LanA (CG10236, FBgn0002526). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: receptor binding. There is experimental evidence for 12 unique biological process terms, many of which group under: system development; post-embryonic organ morphogenesis; immune response; growth; locomotory behavior; cell cycle; cellular component organization or biogenesis; cardiovascular system development; neuromuscular process; biological regulation. 30 alleles are reported. The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: organ system subdivision; organ system; peripheral nervous system; external compound sense organ; adult segment; non-connected developing system; adult; extracellular matrix; adult trachea; late extended germ band embryo. It has one annotated transcript and one annotated polypeptide. Protein features are: Concanavalin A-like lectin/glucanase, subgroup; Concanavalin A-like lectin/glucanases superfamily; EGF-like, conserved site; EGF-like, laminin; Laminin B type IV; Laminin B, subgroup; Laminin G domain; Laminin I; Laminin II; Laminin, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 06-24 hour embryonic stages.

Gene summary for CG10236 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10236:CG10236 is not perturbed in primary screen.
CG10236 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10236.
Cell Count:
CG_NumberCategoryR1R2R3
CG10236Primary screen344772656
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10236:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19153-0.343511243-0.4334868340.4525367630.425735538-0.615454247-1.242430895-0.351531768-1.783218311-1.1587871380.9615869481.6402622250.9786123930.9887832111.087599393-0.474309688-0.6798812461.3987244350.7189788971.321178508-0.9457753480.0383841313.0370242263.47520021
1922030.225538572-0.600054682-0.6372518731.022398099-0.0709189981.2399256571.0161966940.7057859261.15780505-0.6809629232.0642289880.340395934-0.016754717-0.7091260851.8586109290.331304991-0.0012610560.391261897-0.4806286821.0291825342.357654071-0.570728353-0.759433114
193113-0.619828460.111554928-0.145960806-0.1954927931.8048854481.9827242521.5980296122.1995404731.8709496271.417551031.581598736-0.1576855841.5185090741.6209321170.5956438690.2399604691.6079221861.4757527881.5829876922.220879003-0.4223859990.741130253-0.170653411
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10236 is not tested in classification assay
Integrated Annotations for CG10236 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
central nervous system developmentGO:0007417non-traceable author statement
peripheral nervous system development
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
basement membraneGO:0005604inferred from sequence or structural similarity with MGD:Lama1; MGI:MGI:99892
basement membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
receptor bindingGO:0005102inferred from electronic annotation with InterPro:IPR009254
Other annotations
DatabaseLink
FlyBaseClick here to see CG10236 in FlyBase
FLIGHTClick here to see CG10236 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10236 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10236
Entrez GeneEntrez Gene page for CG10236
UniprotUniprot page for CG10236

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)