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Gene Page - CG Number : CG10238
Gene Summary - CG10238:

CG10238: The gene Molybdopterin synthase 2 is referred to in FlyBase by the symbol Dmel\Mocs2 (CG10238, FBgn0039280). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: histone acetyltransferase activity. There is experimental evidence that it is involved in the biological process: histone acetylation; chromatin remodeling. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Beta-grasp domain; Molybdopterin converting factor, subunit 1; Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp; ThiamineS/Molybdopterin converting factor subunit 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.

Gene summary for CG10238 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10238:CG10238 is not perturbed in primary screen.
CG10238 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fclc+ LP_Fint1- LP_Fint2- LP_Fint3- LP_Fint4+ LP_Fmph1- LP_Fmph2- LP_Fmph3- LP_Fnum- Rto1+ Rto2+ Rto3+ SP_Fclc+ SP_Fint2+ SP_Fint3+ SP_Fmph1+ SP_Fmph2+ SP_Fmph3+
CG10238 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10238.
Cell Count:
CG_NumberCategoryR1R2R3
CG10238Primary screen436767638
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10238:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191552.075218843-0.2774950590.1611619340.8572276530.512316040.1339258120.878998114-0.1761792791.3008805793.3875530713.2711320321.1058072783.067688652.7226786171.4516334161.1427665693.5276927282.5409728633.6525194311.0116218333.7518388650.138348867-0.155424775
1922011.6571095290.3792921561.898039301-0.66828870.4779907223.0844880155.2710679582.4866527562.549711769-1.207349965-1.561975166-0.4432731150.7742970871.140933435-0.2299098560.5016704150.77641731.1866305791.2776102983.4287027490.2440708672.3460277376.036543351
193111-0.6419172850.5694667472.191405725-0.5915908421.7269239962.2029133442.6108965372.2457145291.744934305-0.3283816560.5772810050.1042943162.3174070422.1072590521.2552064830.023950552.5106904640.3238486351.8447400072.2147131760.2528222683.4750864622.620147615
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10238Slide14C0.0000.7000.6950.659
CG10238Slide14O0.1711.1131.0531.314
CG10238Slide14P0.0201.2391.1451.201
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10238 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
Mo-molybdopterin cofactor biosynthetic processGO:0006777inferred from sequence or structural similarity with EMBL:AF091872; protein_id:AAD14601
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
molybdopterin synthase complexGO:0019008inferred from sequence or structural similarity with EMBL:AF091872; protein_id:AAD14601
Ada2/Gcn5/Ada3 transcription activator complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG10238 in FlyBase
FLIGHTClick here to see CG10238 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10238 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10238
Entrez GeneEntrez Gene page for CG10238
UniprotUniprot page for CG10238

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)