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Gene Page - CG Number : CG10248
Gene Summary - CG10248:

CG10248: The gene Cytochrome P450-6a8 is referred to in FlyBase by the symbol Dmel\Cyp6a8 (CG10248, FBgn0013772). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: alkane 1-monooxygenase activity. There is experimental evidence that it is involved in the biological process: response to caffeine; insecticide metabolic process; lauric acid metabolic process. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, E-class, group II; Cytochrome P450, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages.

Gene summary for CG10248 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10248:CG10248 is not perturbed in primary screen.
CG10248 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10248.
Cell Count:
CG_NumberCategoryR1R2R3
CG10248Primary screen694873530
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10248:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191650.049072431-0.121728901-0.374768319-0.3860668681.2334824941.7522113261.628716691.8146381842.6960605550.9318269521.776946471-0.3920019831.1237605190.962545515-0.380587480.0992460481.1239818391.1195111151.6121117612.5654848480.2363803314.9717016692.915470712
1922211.660269336-0.119510286-0.7685926090.1314712940.3526172221.001271581.1355126291.1433567491.5222434210.0243048210.025092866-0.5999462991.2080622260.297732153.2009778070.019532692.169511825-0.4420401152.5508102421.136438885-0.4268358031.5727604890.679159768
19371-0.481271582-0.736983811-0.853321515-0.9536849341.0952495951.0223019620.5837641160.7588831231.0472816510.315096729-0.0173664631.4216710140.8833184370.1206710161.4439799780.1708629091.709984363-0.150638171.9506267961.1754675022.0652024021.4283766231.677843421
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10248 is not tested in classification assay
Integrated Annotations for CG10248 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
insecticide metabolic processGO:0017143inferred from direct assay
lauric acid metabolic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
microsomeGO:0005792non-traceable author statement
membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
electron carrier activityGO:0009055inferred from sequence or structural similarity with Cyp6a2
electron carrier activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10248 in FlyBase
FLIGHTClick here to see CG10248 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10248 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10248
Entrez GeneEntrez Gene page for CG10248
UniprotUniprot page for CG10248

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)