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Gene Page - CG Number : CG10250
Gene Summary - CG10250:

CG10250: The gene nautilus is referred to in FlyBase by the symbol Dmel\nau (CG10250, FBgn0002922). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: DNA binding; sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: larval somatic muscle development; determination of muscle attachment site; muscle organ development. 18 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; multicellular structure; anatomical structure; hypodermal muscle of larval abdomen; non-connected developing system; larval abdominal segment; embryonic/larval hypodermal muscle; portion of tissue; cardioblast; extended germ band embryo; A1-7 dorsal oblique muscle 3. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Helix-loop-helix domain; Myogenic basic muscle-specific protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages.

Gene summary for CG10250 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10250:CG10250 is not perturbed in primary screen.
CG10250 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10250.
Cell Count:
CG_NumberCategoryR1R2R3
CG10250Primary screen46911511
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10250:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19167-0.1565891830.7611236070.472538686-0.2325138410.6921685281.2905347361.4102339941.201554341.389912904-0.23853582-0.898969592-0.311237732-1.373340816-1.388496171-0.60373304-0.020255873-1.22447052-0.827242552-1.3973690061.3659358720.3640054091.466436371-0.413497762
192219-1.839332761-1.32670888-1.259388168-0.624024634-4.805401857-10.33661722-6.115960798-9.468599404-11.87038914-1.926231423-2.905634677-0.588825131-3.916533279-2.740310095-0.373516819-2.935436035-3.052919573-5.464940333-3.556785911-10.10991892-0.436801295-1.430239368-0.284071367
19369-0.017271589-0.2898542270.1828138350.2328583631.3767202921.2519872931.0240074751.265666270.935844281-0.869225086-0.2680445150.039953823-0.091628216-0.8031100030.5064794350.472502477-0.236007253-0.2459798060.0961818311.1321527990.093571612.9013598251.81988195
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10250 is not tested in classification assay
Integrated Annotations for CG10250 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of striated muscle tissue developmentGO:0016202traceable author statement
muscle organ development
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634traceable author statement
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700traceable author statement
DNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10250 in FlyBase
FLIGHTClick here to see CG10250 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10250 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10250
Entrez GeneEntrez Gene page for CG10250
UniprotUniprot page for CG10250

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)