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Gene Page - CG Number : CG10255
Gene Summary - CG10255:

CG10255: The gene Lap1 is referred to in FlyBase by the symbol Dmel\Lap1 (CG10255, FBgn0033984). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: Ras GTPase binding. Based on sequence similarity, it is predicted to be involved in the biological process: protein transport; establishment or maintenance of cell polarity. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Leucine rich repeat 4; Leucine-rich repeat; Leucine-rich repeat, typical subtype; PDZ domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages.

Gene summary for CG10255 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10255:CG10255 is not perturbed in primary screen.
CG10255 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10255.
Cell Count:
CG_NumberCategoryR1R2R3
CG10255Primary screen69325524
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10255:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191700.141142840.4797603430.3877728390.4300787321.8029794292.1350128652.9800985092.1063391183.3577118090.7715213911.5838247870.1542875751.2399689321.5048605640.002391114-0.1155314291.7878242061.2855733612.3102684853.4638965762.498982271.267260250.01428784
1922160.46422102-0.9466858320.315483886-0.033360992-4.772651253-9.799609183-6.099932413-11.1378864-11.55431582-2.546988564-3.2306713580.438750605-4.439668882-2.440933622-1.381705906-3.532349192-3.002159667-4.894309513-6.172855-9.347064879-0.517867996-0.738122976-1.842686458
19366-0.437341690.6683957720.5532840730.5720434460.4325498090.2320379830.4663949530.3145564471.02165191.8756136751.295455078-0.4535756412.0053621282.2585287315.3178895950.6906456422.4049839671.1523145462.7141318271.1073319430.5231523732.2796310730.125107492
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10255 is not tested in classification assay
Integrated Annotations for CG10255 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
establishment or maintenance of cell polarityGO:0007163non-traceable author statement
establishment or maintenance of cell polarity
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
adherens junctionGO:0005912inferred from sequence or structural similarity with UniProtKB:O61967
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
Ras GTPase bindingGO:0017016inferred from sequence or structural similarity with EMBL:AF068921
Other annotations
DatabaseLink
FlyBaseClick here to see CG10255 in FlyBase
FLIGHTClick here to see CG10255 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10255 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10255
Entrez GeneEntrez Gene page for CG10255
UniprotUniprot page for CG10255

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)