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Gene Page - CG Number : CG10268
Gene Summary - CG10268:

CG10268: This gene is referred to in FlyBase by the symbol Dmel\CG10268 (FBgn0032811). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphomevalonate kinase activity. It is reported to be involved in the biological process: isoprenoid biosynthetic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Higher eukaryotic phosphomevalonate kinase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages, during early larval stages, during late pupal stages.

Gene summary for CG10268 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10268:CG10268 is perturbed in following parameters in primary screen: CellSize
CG10268 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10268.
Cell Count:
CG_NumberCategoryR1R2R3
CG10268Primary screen478845557
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10268:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19177-0.047907416-0.357106792-0.720714927-0.4358670.5627910261.0241918060.8209551991.0476288521.3499826080.494947551.892813899-0.225622520.6027549420.472410494-0.1931628960.2698724141.2413423230.5149394890.773821591.3412450254.121375041.8712888440.347958571
1922390.7757079321.1430394961.0745615121.6357685420.6245357920.8936776681.3162129860.9390667680.8596793130.5806263881.902844471-0.387389022-0.456452286-0.5227974354.0984832160.752341286-2.0496185191.561342262-3.24048971.2429427374.3292716490.0426784210.611623905
19389-0.582735798-0.0946540140.6062731931.0553579061.6072480811.9279456561.3649673361.924883551.6636531271.5657099921.743892677-0.1736990582.0551005981.1734718462.7757118521.021349081.0221153270.9478700171.3242572921.875245373-0.5029073880.1180173470.691831796
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10268 is not tested in classification assay
Integrated Annotations for CG10268 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
isoprenoid biosynthetic processGO:0008299inferred by curator from GO:0004631
cholesterol biosynthetic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from electronic annotation with InterPro:IPR005919
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
phosphomevalonate kinase activityGO:0004631inferred from sequence or structural similarity with UniProtKB:Q15126
phosphomevalonate kinase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10268 in FlyBase
FLIGHTClick here to see CG10268 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10268 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10268
Entrez GeneEntrez Gene page for CG10268
UniprotUniprot page for CG10268

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)