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Gene Page - CG Number : CG10279
Gene Summary - CG10279:

CG10279: The gene Rm62 is referred to in FlyBase by the symbol Dmel\Rm62 (CG10279, FBgn0003261). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: RNA interference; antimicrobial humoral response; regulation of alternative mRNA splicing, via spliceosome; neurogenesis. 44 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; dorsocentral bristle; mesothoracic tergum; scutellar bristle; egg chamber; pigment cell. It has 12 annotated transcripts and 12 annotated polypeptides. Protein features are: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; RNA helicase, ATP-dependent, DEAD-box, conserved site; RNA helicase, DEAD-box type, Q motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.

Gene summary for CG10279 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10279:CG10279 is perturbed in following parameters in primary screen: Okt Tmph2
CG10279 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10279.
Cell Count:
CG_NumberCategoryR1R2R3
CG10279Primary screen161243252
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10279:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191851.927900562-0.2504727130.795629821.013043849-1.040132498-1.526820408-1.128782857-1.776236659-1.2318751473.4976902161.7676018851.7227333010.3080001780.6176305335.520967051-0.3141517594.4497707484.2294498316.443047242-0.8677683680.365808409-0.3704273351.548819409
1922310.105770016-0.799343625-0.4644681671.105490071-1.925782516-3.576132308-1.384163178-3.766844622-2.8801174310.76009707-1.925856913-1.711830311-3.00731032-1.8740229284.936474842-0.9658425020.5182725851.234331457-1.945980129-2.7527460562.6984660650.0378614923.190849844
193811.194251502-0.4762112910.149632439-1.312571191-0.713226094-0.084298888-0.34152811-0.270789340.1463687562.0493145940.2472626850.482982148-0.305074058-0.5347610981.6110736170.3639677670.4391185013.1962909730.9058963110.6789327511.603830491-0.896355865-0.930272725
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10279 is not tested in classification assay
Integrated Annotations for CG10279 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
RNA interferenceGO:0016246inferred from mutant phenotype
antimicrobial humoral response
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred by curator from GO:0000381
polytene chromosome puff
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with Fmr1
ATP-dependent RNA helicase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10279 in FlyBase
FLIGHTClick here to see CG10279 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10279 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10279
Entrez GeneEntrez Gene page for CG10279
UniprotUniprot page for CG10279

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)