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Gene Page - CG Number : CG1028
Gene Summary - CG1028:

CG1028: The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process: muscle cell fate specification; specification of segmental identity, thorax; heart development; positive regulation of transcription from RNA polymerase II promoter; specification of segmental identity, antennal segment; anterior/posterior axis specification; neuroblast development; lymph gland development. 174 alleles are reported. The phenotypes of these alleles are annotated with 66 unique terms, many of which group under: organ system subdivision; adult segment; organ system; thoracic segment; humeral trabecule; imaginal precursor; cephalopharyngeal skeleton; external compound sense organ; non-connected developing system; embryonic thoracic segment. It has 11 annotated transcripts and 11 annotated polypeptides. Protein features are: Homeobox protein, antennapedia type; Homeobox protein, antennapedia type, conserved site; Homeobox, conserved site; Homeodomain; Homeodomain, metazoa; Homeodomain-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis.

Gene summary for CG1028 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1028:CG1028 is perturbed in following parameters in primary screen: Fmph1 Fmph2 Fmph3 Tmph2
CG1028 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fint1+ LP_Fint2+ LP_Fint3+ LP_Fmph1+ LP_Fmph2+ LP_Fmph3+ LP_Fnum+ NuCellD+(fld) NuFluct+(fld) SP_Fint1+ SP_Fint2+ SP_Fint3+ SP_Fmph1+ SP_Fmph2+ SP_Fmph3+
CG1028 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1028.
Cell Count:
CG_NumberCategoryR1R2R3
CG1028Primary screen375193129
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1028:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1028Slide8C0.0471.2741.2511.180
CG1028Slide8O0.9231.0360.9620.991
CG1028Slide8P0.0081.3721.3211.282
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG1028 :Gene Ontology Annoations: Biological Process
Gene Ontology Annoations: Cellular Component
Gene Ontology Annoations: Molecular Function
Other annotations
DatabaseLink
FlyBaseClick here to see CG1028 in FlyBase
FLIGHTClick here to see CG1028 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1028 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1028
Entrez GeneEntrez Gene page for CG1028
UniprotUniprot page for CG1028

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)