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Gene Page - CG Number : CG10280
Gene Summary - CG10280:

CG10280: This gene is referred to in FlyBase by the symbol Dmel\CG10280 (FBgn0037395). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: metalloendopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Metallopeptidase, catalytic domain; Peptidase M12A, astacin; Peptidase, metallopeptidase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, during early larval stages.

Gene summary for CG10280 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10280:CG10280 is not perturbed in primary screen.
CG10280 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10280.
Cell Count:
CG_NumberCategoryR1R2R3
CG10280Primary screen144864640
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10280:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19186-0.52041364-0.444425948-0.81567068-0.185153471-1.578943305-2.225098292-3.133600976-2.737496133-2.8090460880.5230362630.2988630611.552185484-0.192915354-0.615204114-0.719013945-1.8380054080.146931965-0.570824711-0.344266554-2.8425730141.053651768-0.352606366-0.702982077
1922300.856216723-0.320676472-0.7595069070.0984912560.6246595610.807979430.3096912580.8642292631.175012272-0.5550496350.3210810973.6118638010.9618292180.2971890182.7812557320.3643693530.645406603-0.344900430.9422312320.9820460470.3589148950.0566275850.405548999
19380-0.220634280.2933719471.961822036-0.4949762942.3383427952.8341579312.7802633652.2529260381.7456957640.820671120.7148198130.2616165461.1899216550.5440320232.5691889680.0435711961.7074839990.4871581611.0517100862.529525136-0.557827576-0.120569154-0.214435167
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10280 is not tested in classification assay
Integrated Annotations for CG10280 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
proteolysisGO:0006508inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
metalloendopeptidase activityGO:0004222inferred from sequence or structural similarity with UniProtKB:Q16820
zinc ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10280 in FlyBase
FLIGHTClick here to see CG10280 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10280 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10280
Entrez GeneEntrez Gene page for CG10280
UniprotUniprot page for CG10280

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)