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Gene Page - CG Number : CG10281
Gene Summary - CG10281:

CG10281: The gene Transcription factor IIFα is referred to in FlyBase by the symbol Dmel\TfIIFα (CG10281, FBgn0010282). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: TFIIF-class transcription factor binding. There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription initiation from RNA polymerase II promoter; positive regulation of transcription elongation from RNA polymerase II promoter; neurogenesis. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Transcription Factor IIF, Rap30/Rap74, interaction; Transcription initiation factor IIF, alpha subunit; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10281 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10281:CG10281 is not perturbed in primary screen.
CG10281 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10281.
Cell Count:
CG_NumberCategoryR1R2R3
CG10281Primary screen303586262
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10281:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191882.2335297563.6267017064.1172595051.852520479-1.23561848-0.8224213652.164489702-1.039120216-1.38445622-1.049268183-1.1764250260.0922614190.467794145-0.1580198352.496118765-0.819919156-0.845708674-1.888788484-2.5897553530.2014070040.165097326-0.534491714-0.771045173
1922280.8664023750.8189797810.2557865580.1707121530.7529957051.043511932.4457751380.9534461741.027750043-0.157361871-0.2230043010.452988880.043926759-0.4265377941.6762918730.43937183-0.2161848980.1897739-0.2506988341.3622059881.856019003-0.191188206-0.23552424
193783.3612459472.4815868932.1047079770.497241340.5224532921.588910835.1138141790.664238461.019622235-0.509391432-0.525835495-0.317103942-0.2290817980.2776063630.2674625130.9564747210.6502089271.2200623390.4809595271.380961144-0.413431026-0.673932894-0.63351431
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10281 is not tested in classification assay
Integrated Annotations for CG10281 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transcription initiation from RNA polymerase II promoterGO:0006367inferred from sequence or structural similarity with HGNC_gene:GTF2F1; HGNC:4652; OMIM:189968 AND inferred from sequence or structural similarity with SGD_LOCUS:TFG1; SGD:S0003418
transcription from RNA polymerase II promoter
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
transcription factor TFIIF complexGO:0005674inferred from sequence or structural similarity with HGNC_gene:GTF2F1; HGNC:4652; OMIM:189968 AND inferred from sequence or structural similarity with SGD_LOCUS:TFG1; SGD:S0003418
transcription factor TFIIF complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
TFIIF-class transcription factor bindingGO:0001096inferred from physical interaction with TfIIFβ
DNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10281 in FlyBase
FLIGHTClick here to see CG10281 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10281 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10281
Entrez GeneEntrez Gene page for CG10281
UniprotUniprot page for CG10281

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)