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Gene Page - CG Number : CG10296
Gene Summary - CG10296:

CG10296: The gene Hormone receptor 83 is referred to in FlyBase by the symbol Dmel\Hr83 (CG10296, FBgn0037436). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: steroid hormone receptor activity; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: steroid hormone mediated signaling pathway; regulation of transcription, DNA-dependent. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Nuclear hormone receptor, ligand-binding; Nuclear hormone receptor, ligand-binding, core; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed at stages throughout embryogenesis, during early larval stages, at stages throughout the pupal period, in adult male stages.

Gene summary for CG10296 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10296:CG10296 is not perturbed in primary screen.
CG10296 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10296.
Cell Count:
CG_NumberCategoryR1R2R3
CG10296Primary screen665449260
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10296:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19194-0.3800283990.0131125030.857254266-0.1830943970.1171703930.8290665531.1381971161.3269763122.1454696470.1200287081.207406026-0.4976314470.4945141850.120570812-0.138870584-0.0150807311.3486143862.0916131331.5391507732.960073526-0.1706505097.835330533.527291209
192252-0.499410275-0.034499704-0.482653308-0.2034771490.3054278680.0007053850.303397899-0.0314781620.8199723290.2105752790.4192827180.5313232950.8664159570.594188286-0.1574614880.0807667010.535316760.6393282550.2546995560.851935815-0.2701787820.010891491-0.03585059
193424.2363752281.998296581.2992888410.7502403421.413058161.8372849364.6977496481.2484039710.720839299-0.804754221-0.5878605951.2366181330.4689662750.536386787-0.573703396-0.623248607-0.624693782-0.57060448-0.5093288940.989295057-0.467861204-0.689874783-0.716548847
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10296 is not tested in classification assay
Integrated Annotations for CG10296 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
steroid hormone mediated signaling pathwayGO:0043401inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR008946
regulation of transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity with UniProtKB:P51128
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityGO:0004879inferred from sequence or structural similarity with UniProtKB:P51128
steroid hormone receptor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10296 in FlyBase
FLIGHTClick here to see CG10296 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10296 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10296
Entrez GeneEntrez Gene page for CG10296
UniprotUniprot page for CG10296

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)