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Gene Page - CG Number : CG10306
Gene Summary - CG10306:

CG10306: This gene is referred to in FlyBase by the symbol Dmel\CG10306 (FBgn0034654). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process: translational initiation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-type fold; COP9 signalosome, subunit CSN8; Translation initiation factor 3, subunit 12, N-terminal, eukaryotic; Translation initiation factor 3, subunit 12, eukaryotic; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.

Gene summary for CG10306 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10306:CG10306 is not perturbed in primary screen.
CG10306 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10306.
Cell Count:
CG_NumberCategoryR1R2R3
CG10306Primary screen590621231
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10306:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
19198-0.3823367471.4779534441.649749842-0.2683410640.1155988580.8162869481.1042043760.9893826040.60635454-0.80786907-0.9248037850.2531463570.4645121680.2425874750.389423062-0.388226433-1.746847526-0.772053051-1.6552587091.242797188-0.1581720341.3702103890.956201769
1922481.2752025110.409497525-0.3123727760.145730090.608817330.4863968580.3003131820.4036397110.6702979050.0086394610.178797184-0.0375927270.7539624320.0236973590.3328496620.553290870.2715611680.7687374010.1877636880.5605860680.111443715-0.38593640.688534152
19338-0.3176444011.0015983131.368510333-0.272237193-0.2762318620.030260674-0.777966405-0.36341609-0.8573377760.689297201-0.468756052-0.272232534-0.348132918-0.015998085-0.4879874671.576668686-1.104951911-1.073586445-1.117928679-1.2800560181.3566983-0.058751768-0.417074811
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10306 is not tested in classification assay
Integrated Annotations for CG10306 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
translational initiationGO:0006413inferred from sequence or structural similarity
regulation of translational initiation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
eukaryotic translation initiation factor 3 complexGO:0005852inferred from sequence or structural similarity
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
translation initiation factor activityGO:0003743inferred from sequence or structural similarity
ribosome binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10306 in FlyBase
FLIGHTClick here to see CG10306 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10306 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10306
Entrez GeneEntrez Gene page for CG10306
UniprotUniprot page for CG10306

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)