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Gene Page - CG Number : CG1031
Gene Summary - CG1031:

CG1031: The gene α-Esterase-1 is referred to in FlyBase by the symbol Dmel\α-Est1 (CG1031, FBgn0015568). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: carboxylesterase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Carboxylesterase, type B. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG1031 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1031:CG1031 is perturbed in following parameters in primary screen: Fmph2 Tclc
CG1031 is perturbed in following parameters in classification assay (fluid): LP_Fclc- LP_Fint1+ LP_Fint2+ LP_Fint3+ Okt+(fld) SP_Fint1+ SP_Fint4- SP_Fmph1- SP_Fmph2- SP_Fmph3- SP_Fnum-
CG1031 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1031.
Cell Count:
CG_NumberCategoryR1R2R3
CG1031Primary screen705537253
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1031:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1031Slide19C0.0281.8021.4541.487
CG1031Slide19O0.0572.0491.5251.504
CG1031Slide19P0.2521.4841.0711.084
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG1031 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
-
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
carboxylesterase activityGO:0004091non-traceable author statement
carboxylesterase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG1031 in FlyBase
FLIGHTClick here to see CG1031 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1031 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1031
Entrez GeneEntrez Gene page for CG1031
UniprotUniprot page for CG1031

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)