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Gene Page - CG Number : CG10327
Gene Summary - CG10327:

CG10327: The gene TAR DNA-binding protein-43 homolog is referred to in FlyBase by the symbol Dmel\TBPH (CG10327, FBgn0025790). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: mRNA binding. There is experimental evidence that it is involved in the biological process: negative regulation of synaptic growth at neuromuscular junction; neuron projection morphogenesis; adult locomotory behavior; neuromuscular junction development. 22 alleles are reported. The phenotypes of these alleles are annotated with: eye; embryonic/larval neuromuscular junction; lobe system of mushroom body; ommatidium. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG10327 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10327:CG10327 is not perturbed in primary screen.
CG10327 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10327.
Cell Count:
CG10327Primary screen516337425
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10327:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10327 is not tested in classification assay
Integrated Annotations for CG10327 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
neuromuscular junction developmentGO:0007528inferred from mutant phenotype
adult locomotory behavior
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
mRNA bindingGO:0003729inferred from sequence or structural similarity
nucleic acid binding
Other annotations
FlyBaseClick here to see CG10327 in FlyBase
FLIGHTClick here to see CG10327 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10327 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10327
Entrez GeneEntrez Gene page for CG10327
UniprotUniprot page for CG10327

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)