Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG10335
Gene Summary - CG10335:

CG10335: The gene Porphobilinogen synthase is referred to in FlyBase by the symbol Dmel\Pbgs (CG10335, FBgn0036271). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: porphobilinogen synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: tetrapyrrole biosynthetic process. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Aldolase-type TIM barrel; Porphobilinogen synthase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages.

Gene summary for CG10335 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10335:CG10335 is not perturbed in primary screen.
CG10335 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10335.
Cell Count:
CG_NumberCategoryR1R2R3
CG10335Primary screen576545398
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10335:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1911150.1052446930.9706804670.947250243-0.5272085410.7036189680.6592654020.6899136350.702838870.7173591940.8606980022.5155952921.7948876130.0292937460.7032178390.286956302-0.2918563870.8371880013.0265982751.4969856860.7597472340.8104710240.454971441.016242635
1922611.120991030.0362743610.0527621691.5659123560.4551917381.7461574082.2824604561.496321041.1931797061.1936303220.991572104-0.1305799822.1627907171.4943707120.1107869810.2913682430.4537483930.3771118850.4182652271.532978098-0.10772428-0.357141654-0.287523287
19351-0.0987953950.2630848430.243776591-0.5177130320.7957742470.9139764481.0309165521.0836617491.3813419520.6848007851.7312974870.46291692.1625672431.4741882641.1978867570.7555322161.2754442770.7180134691.1366702831.378484059-0.498865373-0.179530355-0.239518981
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10335 is not tested in classification assay
Integrated Annotations for CG10335 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
tetrapyrrole biosynthetic processGO:0033014inferred from electronic annotation with InterPro:IPR001731
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
porphobilinogen synthase activityGO:0004655inferred from direct assay
porphobilinogen synthase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10335 in FlyBase
FLIGHTClick here to see CG10335 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10335 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10335
Entrez GeneEntrez Gene page for CG10335
UniprotUniprot page for CG10335

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)