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Gene Page - CG Number : CG10346
Gene Summary - CG10346:

CG10346: The gene Grip71 is referred to in FlyBase by the symbol Dmel\Grip71 (CG10346, FBgn0032705). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: gamma-tubulin binding. There is experimental evidence that it is involved in the biological process: centrosome organization; mitosis; mitotic spindle organization; centrosome duplication; regulation of cell cycle. 6 alleles are reported. The phenotypes of these alleles are annotated with: neuroblast; S2 cell-line; spindle. It has one annotated transcript and one annotated polypeptide. Protein features are: WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10346 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10346:CG10346 is not perturbed in primary screen.
CG10346 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10346.
Cell Count:
CG_NumberCategoryR1R2R3
CG10346Primary screen412386420
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10346:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1911210.8817133381.1833085611.068898906-0.276521338-1.431388049-0.076010232.638732378-0.079953602-0.13547264-1.0268166621.733043237-1.076000706-0.226030480.4989820950.116049058-0.651668088-1.486317306-0.860664551-2.0611122751.4595704980.201303944-0.777557913-0.464526792
1922850.2303674380.192137522-0.2835607080.8463560710.0323703220.2805390931.6649129270.1219213120.230911585-0.0797762340.1945269730.317600348-0.0721791990.710248738-0.2205025270.0313159910.3966114150.463499507-0.1348663920.4114746910.472907892-0.514682586-0.451680324
19315-0.241399450.3490548871.0990528860.4640559181.1617131242.006467754.0430477991.475165711.9947716781.0258876221.909706434-0.3018905691.3801787151.5243029591.5866052991.4028294941.2708512761.0588375231.3910359442.397341005-0.600461399-0.259526149-0.42437098
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10346 is not tested in classification assay
Integrated Annotations for CG10346 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
mitosisGO:0007067inferred from mutant phenotype
regulation of cell cycle
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
gamma-tubulin ring complexGO:0008274non-traceable author statement
gamma-tubulin ring complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
gamma-tubulin bindingGO:0043015inferred from direct assay
Other annotations
DatabaseLink
FlyBaseClick here to see CG10346 in FlyBase
FLIGHTClick here to see CG10346 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10346 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10346
Entrez GeneEntrez Gene page for CG10346
UniprotUniprot page for CG10346

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)