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Gene Page - CG Number : CG10354
Gene Summary - CG10354:

CG10354: This gene is referred to in FlyBase by the symbol Dmel\Rat1 (CG10354, FBgn0031868). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: 5'-3' exonuclease activity; 5'-3' exoribonuclease activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 9 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: 5'-3' exoribonuclease 2; Putative 5-3 exonuclease. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG10354 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10354:CG10354 is not perturbed in primary screen.
CG10354 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10354.
Cell Count:
CG_NumberCategoryR1R2R3
CG10354Primary screen865901315
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10354:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191125-0.3646671560.6932960311.055626913-0.2129736441.4406831440.7574863650.1815440810.8725449431.121133688-0.7300448820.6651541951.390325571-0.10067597-0.132111193-0.6076316180.9205862530.2855435971.3143138450.0710164530.818453725-0.097544065.0180637442.544043714
1922810.683614711.0910701150.754126231-0.3094660751.3593157561.9945452982.0681820691.2043982061.9704170491.3962072221.4999297020.1210540934.110861433.984864680.6202146631.4537542621.6029807851.4970665611.7478876452.098057810.1914347792.1040490833.785382943
193114.3511648322.3911634321.0347026250.729601440.5058250550.7242906514.7404089270.7981071470.8599227641.0887279421.3116810991.3884161790.8665058670.9759296240.743442981.048411701-0.063295128-0.1158025570.1774909481.190473784-0.3184675970.131477517-0.089293045
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10354 is not tested in classification assay
Integrated Annotations for CG10354 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
DNA catabolic process, exonucleolyticGO:0000738inferred from sequence or structural similarity with UniProtKB:Q9H0D6
neurogenesis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleolusGO:0005730inferred from sequence or structural similarity with UniProtKB:Q9H0D6
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
5'-3' exoribonuclease activityGO:0004534inferred from sequence or structural similarity with UniProtKB:P40848
5'-3' exonuclease activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10354 in FlyBase
FLIGHTClick here to see CG10354 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10354 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10354
Entrez GeneEntrez Gene page for CG10354
UniprotUniprot page for CG10354

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)