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Gene Page - CG Number : CG10357
Gene Summary - CG10357:

CG10357: This gene is referred to in FlyBase by the symbol Dmel\CG10357 (FBgn0035453). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: triglyceride lipase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: lipid metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Lipase; Lipase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed during late pupal stages, in stages of adults of both sexes.

Gene summary for CG10357 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10357:CG10357 is perturbed in following parameters in primary screen: Fmph2 NuCirc
CG10357 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fclc- Rto3+ SP_Fint1+ SP_Fint2+ SP_Fint3+ SP_Fmph1+
CG10357 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10357.
Cell Count:
CG_NumberCategoryR1R2R3
CG10357Primary screen76088329
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10357:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1911271.4762645584.7181088135.4344169161.1167681141.1042095982.9606902417.4727164952.9168186433.690929890.058723068-0.0601907114.0095242782.3127638841.4914557330.4630661870.9194766471.2910729073.7269165572.0418957845.8086219741.3774211879.8935883333.628071827
192279-0.285444563-0.7277455361.1191445454.112405095-1.2051325350.868893185-1.7533036480.483709544-2.682385268-1.778652509-0.497178194-0.720144701-2.074483299-0.6830789061.1320436696.758434912-1.0702667-2.027850894-0.514564454-2.4147413812.126101740.4979560243.70485855
19394.8580759432.4228995492.7489869120.4192932080.9917661622.378745784.9215447321.3784686911.410796950.1840847210.890856945-0.8914868911.3812728240.943603611-0.0414870550.2497595260.7954639480.2908576960.7047309041.501927789-0.32526122-0.2450771630.121955612
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10357Slide8C0.9650.9740.8511.159
CG10357Slide8O0.2291.1090.9891.090
CG10357Slide8P0.0071.2571.2211.304
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10357 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
lipid metabolic processGO:0006629inferred from electronic annotation with InterPro:IPR000734
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
triglyceride lipase activityGO:0004806inferred from sequence or structural similarity with UniProtKB:Q02157
Other annotations
DatabaseLink
FlyBaseClick here to see CG10357 in FlyBase
FLIGHTClick here to see CG10357 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10357 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10357
Entrez GeneEntrez Gene page for CG10357
UniprotUniprot page for CG10357

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)