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Gene Page - CG Number : CG10363
Gene Summary - CG10363:

CG10363: The gene Thioester-containing protein 4 is referred to in FlyBase by the symbol Dmel\Tep4 (CG10363, FBgn0041180). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: peptidase inhibitor activity. There is experimental evidence that it is involved in the biological process: multicellular organism reproduction; antibacterial humoral response. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: A-macroglobulin complement component; Alpha-2-macroglobulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, conserved site; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin, receptor-binding; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.

Gene summary for CG10363 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10363:CG10363 is not perturbed in primary screen.
CG10363 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10363.
Cell Count:
CG_NumberCategoryR1R2R3
CG10363Primary screen6641180368
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10363:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191133-0.756770172-0.043222753-0.273906704-0.6697958550.7291134861.6995932870.3417425261.0855906142.1697628580.2479748191.2991150870.095358653-0.099964186-0.273687812-0.293647248-0.2971731042.4142256385.5141412721.4934448372.109850797-0.5960654035.1514912712.305493934
1922730.2146956630.7136930323.1412398618.26231119614.815263596.5704811642.2055332665.812315865-0.4913375642.3633155911.5266913490.0090472590.048970772-0.1092457874.75018427721.416536064.658971680.1667680583.267452808-0.8585128427.340874446-1.692073997-1.160665325
1933-0.76847362-0.2082856340.2641566190.0163818421.2204458981.6664150063.4894234411.1150491051.448207424-0.1900839090.2547617940.3389022170.29954769-0.099343436-0.6161231680.353673950.3460865690.1891026060.7293655251.485261324-0.5012286020.072309067-0.113096013
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10363 is not tested in classification assay
Integrated Annotations for CG10363 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
antibacterial humoral responseGO:0019731inferred from direct assay
multicellular organism reproduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
extracellular spaceGO:0005615inferred from electronic annotation with InterPro:IPR011626
extracellular space
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
peptidase inhibitor activityGO:0030414inferred from sequence or structural similarity with MGD:A2m; MGI:MGI:87854
endopeptidase inhibitor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10363 in FlyBase
FLIGHTClick here to see CG10363 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10363 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10363
Entrez GeneEntrez Gene page for CG10363
UniprotUniprot page for CG10363

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)