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Gene Page - CG Number : CG10369
Gene Summary - CG10369:

CG10369: The gene Inwardly rectifying potassium channel 3 is referred to in FlyBase by the symbol Dmel\Irk3 (CG10369, FBgn0032706). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: inward rectifier potassium channel activity. There is experimental evidence that it is involved in the biological process: wing disc development. 5 alleles are reported. The phenotypes of these alleles are annotated with: wing; wing vein; wing hinge. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Immunoglobulin E-set; Potassium channel, inwardly rectifying, Kir; Potassium channel, inwardly rectifying, Kir, cytoplasmic. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages, during early larval stages, in stages of adults of both sexes.

Gene summary for CG10369 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10369:CG10369 is not perturbed in primary screen.
CG10369 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10369.
Cell Count:
CG_NumberCategoryR1R2R3
CG10369Primary screen734465315
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10369:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191137-0.0406924130.1966727132.8607187340.8153905850.4093006651.1611012943.8771795931.4778591253.2679921671.2162637651.0778098353.4281460162.0542057641.245721051-0.015624631-0.2835495871.2742161076.0484208061.1960693994.3515468430.10229777110.572269996.413480618
1922990.5545739380.552554499-0.008492901-0.1902845250.5718230951.0809269172.6754126341.2057011771.730907743-0.1666853851.1213898790.4232661470.520615618-0.18567506-0.4602572970.4497034690.7058283911.9412428510.6165872531.784443409-0.4594135340.3451015510.072524
19329-0.1708313280.009316711-0.65675051-0.1200629020.1957289210.3320124410.3469825470.443914740.1015876280.415107370.462072431-0.1912373850.360066685-0.1574609110.073242688-0.3063847960.740673590.154388060.0996659170.494065741-0.680106804-0.28141106-0.56564592
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10369 is not tested in classification assay
Integrated Annotations for CG10369 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
potassium ion transportGO:0006813inferred from sequence or structural similarity with Ir
regulation of membrane potential
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from sequence or structural similarity with Ir
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
inward rectifier potassium channel activityGO:0005242non-traceable author statement
inward rectifier potassium channel activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10369 in FlyBase
FLIGHTClick here to see CG10369 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10369 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10369
Entrez GeneEntrez Gene page for CG10369
UniprotUniprot page for CG10369

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)