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Gene Page - CG Number : CG10373
Gene Summary - CG10373:

CG10373: The gene Jwa ortholog is referred to in FlyBase by the symbol Dmel\Jwa (CG10373, FBgn0032704). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: ion channel activity. There is experimental evidence that it is involved in the biological process: response to ethanol. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Chloride channel, core; Prenylated rab acceptor PRA1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG10373 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10373:CG10373 is not perturbed in primary screen.
CG10373 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10373.
Cell Count:
CG_NumberCategoryR1R2R3
CG10373Primary screen536277407
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10373:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191143-0.622208309-0.5608066880.405902012-0.1222973860.631213093-1.07728005-0.953214834-2.097942172-0.595419535-1.2016074360.277077808-0.2921918530.8238852150.5489437852.5046573230.060934183-0.2644127310.986371611-0.36884876-0.634641954-0.554173418.0986066193.130090643
192293-0.379704506-0.522712105-0.244550708-0.713331883-0.20265551-0.415552833-0.732247462-0.603063581-0.296425705-0.476505173-0.322694799-0.5525100530.0855690770.120185821-0.82033511-0.529752223-0.396451778-0.285885016-0.605534737-0.238242898-0.181213807-0.231950846-0.373659576
19323-0.6900104530.3421531230.531548475-0.9109264441.0486272671.3619162853.2068435851.3311628791.634598358-0.2936687440.008734992-0.5081289960.6479520820.4343788020.7002436210.3786719680.9185051250.1442379420.9929853991.542309877-0.4706927170.5087978540.747625519
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10373 is not tested in classification assay
Integrated Annotations for CG10373 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
response to ethanolGO:0045471inferred from mutant phenotype
transmembrane transport
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cellular_componentGO:0005575no biological data available
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ion channel activityGO:0005216inferred from electronic annotation with InterPro:IPR014743
Other annotations
DatabaseLink
FlyBaseClick here to see CG10373 in FlyBase
FLIGHTClick here to see CG10373 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10373 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10373
Entrez GeneEntrez Gene page for CG10373
UniprotUniprot page for CG10373

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)