.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10387Gene Summary - CG10387:CG10387: The gene tosca is referred to in FlyBase by the symbol Dmel\tos (CG10387, FBgn0015553). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: exodeoxyribonuclease I activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: DNA repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 5'-3' exonuclease, C-terminal domain; DNA repair protein (XPGC)/yeast Rad; Helix-hairpin-helix motif, class 2; XPG N-terminal; XPG conserved site; XPG/RAD2 endonuclease. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. Gene summary for CG10387 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10387:CG10387 is not perturbed in primary screen. CG10387 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10387.Cell Count:CG_NumberCategoryR1R2R3CG10387Primary screen642493318R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10387: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize191153-0.0500780360.27709029-0.529409253-0.4223577120.3071317740.8901001450.9056598271.0310901310.1405852090.316946589-0.115604361-0.347655243-0.844521487-0.711438921-0.2656353910.544715198-1.651948466-0.430566773-2.8335528010.985169843-0.2965140530.17719262-0.714869838192133-1.115251756-0.250628108-0.108463949-0.4616611961.1825895910.032607557-0.0118839730.3072383260.1176089320.0077438620.412924060.0462613450.2754979671.024871044-0.4680495511.144227257-0.0054299790.164031523-0.0172459820.437444679-0.212257374-0.0398278770.3548087251932832.085550909-0.029726119-0.168301023-0.5846945150.429755920.6032146270.9350874660.70304510.9800376440.5103359661.598437461.8942925163.3311315911.4173745381.281960490.2375225020.9860622540.5333769340.7914187291.0169679210.3515670120.6938368620.505877071 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10387 is not tested in classification assayIntegrated Annotations for CG10387 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidenceDNA repairGO:0006281inferred from electronic annotation with InterPro:IPR006084, InterPro:IPR006085, InterPro:IPR006086Gene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidence-Gene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceexodeoxyribonuclease I activityGO:0008852inferred from sequence or structural similarity with UniProtKB:P53695 nuclease activity Other annotations DatabaseLinkFlyBaseClick here to see CG10387 in FlyBaseFLIGHTClick here to see CG10387 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10387 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10387Entrez GeneEntrez Gene page for CG10387UniprotUniprot page for CG10387 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10387Gene Summary - CG10387:CG10387: The gene tosca is referred to in FlyBase by the symbol Dmel\tos (CG10387, FBgn0015553). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: exodeoxyribonuclease I activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: DNA repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 5'-3' exonuclease, C-terminal domain; DNA repair protein (XPGC)/yeast Rad; Helix-hairpin-helix motif, class 2; XPG N-terminal; XPG conserved site; XPG/RAD2 endonuclease. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. Gene summary for CG10387 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10387:CG10387 is not perturbed in primary screen. CG10387 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10387.Cell Count:CG_NumberCategoryR1R2R3CG10387Primary screen642493318R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10387: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize191153-0.0500780360.27709029-0.529409253-0.4223577120.3071317740.8901001450.9056598271.0310901310.1405852090.316946589-0.115604361-0.347655243-0.844521487-0.711438921-0.2656353910.544715198-1.651948466-0.430566773-2.8335528010.985169843-0.2965140530.17719262-0.714869838192133-1.115251756-0.250628108-0.108463949-0.4616611961.1825895910.032607557-0.0118839730.3072383260.1176089320.0077438620.412924060.0462613450.2754979671.024871044-0.4680495511.144227257-0.0054299790.164031523-0.0172459820.437444679-0.212257374-0.0398278770.3548087251932832.085550909-0.029726119-0.168301023-0.5846945150.429755920.6032146270.9350874660.70304510.9800376440.5103359661.598437461.8942925163.3311315911.4173745381.281960490.2375225020.9860622540.5333769340.7914187291.0169679210.3515670120.6938368620.505877071 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10387 is not tested in classification assayIntegrated Annotations for CG10387 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidenceDNA repairGO:0006281inferred from electronic annotation with InterPro:IPR006084, InterPro:IPR006085, InterPro:IPR006086Gene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidence-Gene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceexodeoxyribonuclease I activityGO:0008852inferred from sequence or structural similarity with UniProtKB:P53695 nuclease activity Other annotations DatabaseLinkFlyBaseClick here to see CG10387 in FlyBaseFLIGHTClick here to see CG10387 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10387 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10387Entrez GeneEntrez Gene page for CG10387UniprotUniprot page for CG10387
CG10387: The gene tosca is referred to in FlyBase by the symbol Dmel\tos (CG10387, FBgn0015553). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: exodeoxyribonuclease I activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: DNA repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 5'-3' exonuclease, C-terminal domain; DNA repair protein (XPGC)/yeast Rad; Helix-hairpin-helix motif, class 2; XPG N-terminal; XPG conserved site; XPG/RAD2 endonuclease. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)