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Gene Page - CG Number : CG10388
Gene Summary - CG10388:

CG10388: The gene Ultrabithorax is referred to in FlyBase by the symbol Dmel\Ubx (CG10388, FBgn0003944). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; RNA polymerase II distal enhancer sequence-specific DNA binding; sequence-specific DNA binding; protein domain specific binding; DNA binding. There is experimental evidence for 17 unique biological process terms, many of which group under: biological regulation; system development; cell fate commitment; regulation of developmental process; cellular process; appendage development; multicellular organismal development; regulation of RNA metabolic process; mesoderm morphogenesis; renal tubule development; somatic muscle development; post-embryonic organ morphogenesis; specification of organ identity; open tracheal system development; muscle cell differentiation; segment specification; cardiovascular system development. 497 alleles are reported. The phenotypes of these alleles are annotated with 119 unique terms, many of which group under: organ system subdivision; adult segment; organ system; thoracic segment; larval abdominal segment; hypodermal muscle of larval abdomen; non-connected developing system; A1-7 transverse muscle; embryonic thoracic segment; imaginal precursor. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Homeobox protein, antennapedia type, conserved site; Homeobox, conserved site; Homeodomain; Homeodomain, metazoa; Homeodomain-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, during early pupal stages.

Gene summary for CG10388 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10388:CG10388 is not perturbed in primary screen.
CG10388 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10388.
Cell Count:
CG_NumberCategoryR1R2R3
CG10388Primary screen696705226
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10388:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191154-0.083501503-0.3333177631.510378517-0.508074857-0.0432349140.9854483712.1644323131.4171961481.6642499231.2860274530.181653093-0.5151460150.1544094510.055445795-0.260754325-0.0574632910.1667690710.0591041510.7637722972.307665076-0.1988367624.7786831024.446154038
1921320.3186457730.0614825320.095308536-0.3510076161.0480646241.0262592090.7999648390.8442232431.4020531620.4671414470.5941942170.1767736171.4499994880.2167705581.1744831240.646299341.5255363081.2413209131.0579725841.4265883670.0871151270.8755052870.421455211
1932820.504813506-0.3100365770.200999110.856198502-0.373589722-0.1646027341.418347532-0.197781831-0.1888901961.2197090850.561637636-0.5731832770.454566820.3555638430.271878635-0.615487324-0.107347433-0.038609876-0.23553864-0.6638627711.495003187-0.7783557320.404470099
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10388 is not tested in classification assay
Integrated Annotations for CG10388 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
specification of segmental identity, thoraxGO:0007384inferred from mutant phenotype
regulation of transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from direct assay
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with DIP1
sequence-specific DNA binding transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10388 in FlyBase
FLIGHTClick here to see CG10388 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10388 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10388
Entrez GeneEntrez Gene page for CG10388
UniprotUniprot page for CG10388

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)