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Gene Page - CG Number : CG10390
Gene Summary - CG10390:

CG10390: The gene meiosis I arrest is referred to in FlyBase by the symbol Dmel\mia (CG10390, FBgn0014342). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: male meiosis I; spermatid differentiation; regulation of gene expression; spermatogenesis. 9 alleles are reported. The phenotypes of these alleles are annotated with: testis; spermatocyte. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Domain of unknown function DUF1546. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages.

Gene summary for CG10390 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10390:CG10390 is perturbed in following parameters in primary screen: Fmph2
CG10390 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fint4- Okt+(fld) Rto1+ SP_Fint1+
CG10390 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10390.
Cell Count:
CG_NumberCategoryR1R2R3
CG10390Primary screen513619200
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10390:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1911551.3423411782.3762365551.948647025-0.378764188-0.9935478140.4356923424.9507395470.5710028810.520347339-0.855321981-0.9763010221.2065127931.441360984-0.2325166590.8332093160.21491657-1.021991906-1.639285166-2.5710648841.3940438342.0904766220.070674143-0.332407708
1921310.26538530.0302311590.085241379-0.3712698070.7994983730.7652380211.1094456050.5852536661.4683422110.9456087161.374270702-0.4174592371.383580421.1865198560.3804452511.0940464251.4442584511.1998438551.2409241731.7115682870.226789418-0.209817345-0.464480136
19328112.729604739.7649475797.4344026352.5389075521.4704451433.0357378917.4105947581.4116383920.5256949590.417937181.19711115-0.3839089460.4692462370.02943753-0.3232180050.697606919-0.073258331.030932124-0.1786973472.2310428510.243261971-0.14477158-0.428425941
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10390Slide19C0.9021.0831.1150.841
CG10390Slide19O0.0291.4941.5601.930
CG10390Slide19P0.9961.1001.0500.852
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10390 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transcription initiation from RNA polymerase II promoterGO:0006367inferred from sequence or structural similarity with HGNC_gene:TAF6L; HGNC:17305; OMIM:602946 AND inferred from sequence or structural similarity with SGD_LOCUS:TAF60; SGD:S0003080
male meiosis I
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
transcription factor TFIID complexGO:0005669inferred from sequence or structural similarity with HGNC_gene:TAF6L; HGNC:17305; OMIM:602946 AND inferred from sequence or structural similarity with SGD_LOCUS:TAF60; SGD:S0003080
nucleolus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG10390 in FlyBase
FLIGHTClick here to see CG10390 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10390 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10390
Entrez GeneEntrez Gene page for CG10390
UniprotUniprot page for CG10390

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)