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Gene Page - CG Number : CG10399
Gene Summary - CG10399:

CG10399: This gene is referred to in FlyBase by the symbol Dmel\CG10399 (FBgn0031877). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: hydroxymethylglutaryl-CoA lyase activity. Based on sequence similarity, it is predicted to be involved in the biological process: leucine metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Aldolase-type TIM barrel; Pyruvate carboxyltransferase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed during early larval stages.

Gene summary for CG10399 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10399:CG10399 is not perturbed in primary screen.
CG10399 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10399.
Cell Count:
CG_NumberCategoryR1R2R3
CG10399Primary screen5365212
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10399:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191160-0.098846581-0.723276141-0.470257552-0.579027099-0.777252331.4393201550.9293288371.5149593771.436476766-0.2247893540.5061527011.4833290010.7814033640.8258651-0.56720671-0.2692770812.0438221881.3918496143.0271854582.817993370.407542106-0.059758807-0.525048067
1921261.094702581-1.873179819-1.051998381-0.840435871-2.568291823-1.079119977-1.299812879-0.45261043-2.1633521560.206407922-2.000997119-0.8857460740.41985819-0.3084803181.343844245-2.112251168-2.158056692-0.861780144-1.101910089-2.652717799-0.847504949-1.692073997-1.160665325
1932761.3395174443.378800892.481955702-0.208019215-0.2630114431.135941712.7297002620.4851890520.5372836073.6447087851.397860189-0.7495299982.0015809611.3865404010.6822929262.5455850782.485838063.1204179192.3760874080.811362698-0.319651478-0.190836375-0.656679859
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10399 is not tested in classification assay
Integrated Annotations for CG10399 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
leucine metabolic processGO:0006551inferred from sequence or structural similarity with UniProtKB:P35914
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
mitochondrial matrixGO:0005759inferred from sequence or structural similarity with UniProtKB:P35914
microtubule associated complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
hydroxymethylglutaryl-CoA lyase activityGO:0004419inferred from sequence or structural similarity with UniProtKB:P35914
Other annotations
DatabaseLink
FlyBaseClick here to see CG10399 in FlyBase
FLIGHTClick here to see CG10399 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10399 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10399
Entrez GeneEntrez Gene page for CG10399
UniprotUniprot page for CG10399

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)