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Gene Page - CG Number : CG10405
Gene Summary - CG10405:

CG10405: This gene is referred to in FlyBase by the symbol Dmel\CG10405 (FBgn0038431). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: serine-type endopeptidase activity. It is reported to be involved in the biological process: proteolysis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.

Gene summary for CG10405 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10405:CG10405 is not perturbed in primary screen.
CG10405 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) CellSize-(fld) LP_Fint1- LP_Fint1- LP_Fint2- LP_Fint3- LP_Fint4+ NuCellD-(fld) NuFluct-(fld) Okt+(fld) Rto1+ Rto2+ Rto3+ Rto3- SP_Fint1- SP_Fint4+ SP_Fnum-
CG10405 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10405.
Cell Count:
CG_NumberCategoryR1R2R3
CG10405Primary screen408131661
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10405:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191163-0.85505013-0.059354016-0.090636287-0.951235301-0.317505393-0.3667679640.546810389-0.250278631-1.149547279-0.44142642-1.2949051480.999771697-0.7567463910.132672965-0.481319018-1.058293781-2.065966349-1.616356576-1.864028424-0.7307736940.549620970.530024211-0.431010285
1921230.026610581.3880838432.1668602977.77781904614.697970565.4042631443.0836173385.895653217-0.5306650143.29681640.7858505542.7136222780.1497479410.5488224473.37929509921.336987512.341702580.0074073772.817963874-0.8626894465.720538692-3.533772606-4.303791552
1932730.8068523155.4542754966.097718603-1.839543348-3.511750404-3.905170733-1.054040319-3.786363809-4.932641914-3.484957866-1.943875156-0.152874318-2.235016887-2.2216226220.285478793-3.648918739-4.422384789-2.789456716-6.329474535-5.622849672-0.440176499-0.6223817511.137353317
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10405Slide14C0.0030.5700.6720.731
CG10405Slide14O0.0181.1461.2351.299
CG10405Slide14P0.1741.1111.1991.620
CG10405Slide4C0.6940.6601.0261.009
CG10405Slide4O0.5020.8351.2931.249
CG10405Slide4P0.4080.6430.9510.922
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10405 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
proteolysisGO:0006508non-traceable author statement
proteolysis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
serine-type endopeptidase activityGO:0004252non-traceable author statement
serine-type endopeptidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10405 in FlyBase
FLIGHTClick here to see CG10405 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10405 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10405
Entrez GeneEntrez Gene page for CG10405
UniprotUniprot page for CG10405

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)