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Gene Page - CG Number : CG10415
Gene Summary - CG10415:

CG10415: The gene Transcription factor IIEα is referred to in FlyBase by the symbol Dmel\TfIIEα (CG10415, FBgn0015828). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: TFIIEalpha/SarR/Rpc3 HTH domain; Transcription factor TFE/TFIIEalpha HTH domain; Transcription factor TFIIE alpha subunit, C-terminal; Transcription factor TFIIE, alpha subunit; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.

Gene summary for CG10415 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10415:CG10415 is not perturbed in primary screen.
CG10415 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10415.
Cell Count:
CG_NumberCategoryR1R2R3
CG10415Primary screen760289309
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10415:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191171-0.5828456024.9193978974.9604370471.2757716920.5888702972.429740555.4772316361.7983941773.5562178072.682930999-0.056783086-0.5895282872.5836284143.053900540.13327845-0.1508437191.6234069164.2278877341.9860699235.0132974840.5275224748.7584417685.018600411
192145-0.205418128-0.4111280.222427544-0.136175611-0.3099148640.005594640.649446728-0.2946125920.239185050.1330982310.3090434520.7461720041.1658580381.673296370.388836847-0.2994349590.6709197720.4878715970.5940584910.5474695-0.2897754910.1706902660.305938515
1932950.606391011-0.061374268-0.2163173231.296569333-0.0523613790.077854693-0.3712687980.090504736-2.011106939-0.895062920.4238260831.97968086-0.337222187-0.738364612-0.4116958450.20866824-1.070825080.043819516-1.30413531-2.028394353-0.52744542-0.3927128921.465678555
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10415 is not tested in classification assay
Integrated Annotations for CG10415 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transcription initiation from RNA polymerase II promoterGO:0006367inferred from sequence or structural similarity with EMBL:Y08816; protein_id:CAA70050.2 AND inferred from sequence or structural similarity with HGNC_gene:GTF2E1; HGNC:4650; OMIM:189962 AND inferred from sequence or structural similarity with SGD_LOCUS:TFA1; SGD:S0001511
positive regulation of transcription from RNA polymerase II promoter
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
transcription factor TFIIE complexGO:0005673inferred from sequence or structural similarity with EMBL:Y08816; protein_id:CAA70050.2 AND inferred from sequence or structural similarity with HGNC_gene:GTF2E1; HGNC:4650; OMIM:189962 AND inferred from sequence or structural similarity with SGD_LOCUS:TFA1; SGD:S0001511
transcription factor TFIIE complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA bindingGO:0043565inferred from electronic annotation with InterPro:IPR017919
Other annotations
DatabaseLink
FlyBaseClick here to see CG10415 in FlyBase
FLIGHTClick here to see CG10415 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10415 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10415
Entrez GeneEntrez Gene page for CG10415
UniprotUniprot page for CG10415

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)