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Gene Page - CG Number : CG10418
Gene Summary - CG10418:

CG10418: This gene is referred to in FlyBase by the symbol Dmel\CG10418 (FBgn0036277). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: regulation of alternative mRNA splicing, via spliceosome; neurogenesis. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Like-Sm (LSM) domain; Ribonucleoprotein LSM domain; Ribonucleoprotein LSM domain, eukaryotic/archaea-type; U6 snRNA-associated Sm-like protein LSm2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.

Gene summary for CG10418 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10418:CG10418 is perturbed in following parameters in primary screen: Tmph2
CG10418 is not tested in classification assay (fluid).
CG10418 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fint1+
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10418.
Cell Count:
CG_NumberCategoryR1R2R3
CG10418Primary screen702486322
CG10418Secondary assay621924902
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10418:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1911730.1157122583.042055793.8133931360.6496927170.558273252.6275716385.3584759221.3829068193.629973085-0.6995121190.905282755-0.2095195321.3381169041.5022752572.6259621490.2921628521.9216048985.7687648522.6038131385.107105123-0.3920867848.7358562552.74171197
1921430.06600017-0.362743884-0.1005133591.14342660.5443784751.6669254740.6800192051.1145481081.0671744670.0657801330.200078751-0.3650423681.034317620.649846054-0.2581432980.3912305532.4838451511.5448170571.0572399161.1960924320.039935738-0.314580058-0.342327656
193293-0.5942643371.6111873090.207862119-0.3230773620.3313514050.9820830042.1799795750.7793660141.990404180.966930139-0.024507942-0.1663940591.1813411760.89693902-0.2547183643.2736636411.8322318074.0416681181.5193133412.44477361-0.7085398530.0209940220.588515029
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10418Slide10F0.0011.2591.3781.307
CG10418Slide10O0.1400.9100.7220.929
CG10418Slide10T0.2960.9210.9680.833
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10418 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
nuclear mRNA splicing, via spliceosomeGO:0000398inferred from sequence or structural similarity with SGD_LOCUS:LSM2; SGD:S0000122 AND inferred from sequence or structural similarity with protein_id:AAD56226
regulation of alternative nuclear mRNA splicing, via spliceosome
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
small nuclear ribonucleoprotein complexGO:0030532inferred from sequence or structural similarity with EMBL:U85207
spliceosomal complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG10418 in FlyBase
FLIGHTClick here to see CG10418 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10418 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10418
Entrez GeneEntrez Gene page for CG10418
UniprotUniprot page for CG10418

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)