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Gene Page - CG Number : CG10425
Gene Summary - CG10425:

CG10425: This gene is referred to in FlyBase by the symbol Dmel\CG10425 (FBgn0039304). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glucose/ribitol dehydrogenase; NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.

Gene summary for CG10425 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10425:CG10425 is perturbed in following parameters in primary screen: Tint2 Tmph3
CG10425 is not tested in classification assay (fluid).
CG10425 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fint4- Tint1+ Tint4- Tmph1- Tmph2- Tmph3- Tnum-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10425.
Cell Count:
CG_NumberCategoryR1R2R3
CG10425Primary screen347532343
CG10425Secondary assay116213851574
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10425:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191177-0.5307119140.4411870250.1358568340.169088842-1.211947908-0.471578575-0.106649272-0.5826312341.058883852.8747670161.7568733070.1164837581.0678945230.7565126240.545558654-0.3118187173.3868420036.2969356416.1838398140.981283232-0.8926874481.4288482890.102299977
1921390.516449716-0.124534529-0.476186525-0.3715692641.1284618441.5349971432.1367779731.1424834091.238300340.9756614510.505850995-0.3862262010.9348008661.1587018580.0732311590.6181670250.4405506330.5504301250.409970631.566605003-0.1896364230.248703252-0.293084293
193289-0.563868461-0.3271031620.7386354640.286008791.2715630532.0215716384.3773945371.1015510861.9413570294.2613586353.927246449-0.3630543994.81226933.2101020121.3921588543.4537263572.9311266472.5686276953.6853109412.657622892-0.040171718-0.3847227960.250931149
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10425Slide1F0.5900.9460.9261.046
CG10425Slide1O0.5911.0130.9351.206
CG10425Slide1T0.2620.8720.8281.026
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10425 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
metabolic processGO:0008152inferred from electronic annotation with InterPro:IPR002198
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
oxidoreductase activityGO:0016491inferred from sequence or structural similarity with EMBL:X64131; protein_id:CAA45490
nucleotide binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10425 in FlyBase
FLIGHTClick here to see CG10425 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10425 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10425
Entrez GeneEntrez Gene page for CG10425
UniprotUniprot page for CG10425

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)