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Gene Page - CG Number : CG10445
Gene Summary - CG10445:

CG10445: This gene is referred to in FlyBase by the symbol Dmel\CG10445 (FBgn0037531). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; ATP binding; helicase activity. There is experimental evidence that it is involved in the biological process: regulation of alternative mRNA splicing, via spliceosome. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; SNF2-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.

Gene summary for CG10445 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10445:CG10445 is not perturbed in primary screen.
CG10445 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10445.
Cell Count:
CG_NumberCategoryR1R2R3
CG10445Primary screen59795290
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10445:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191188-0.568545393-0.360422220.512408135-0.953460118-0.4286254840.7195067381.3924109420.9237759161.089754896-0.911996162-0.8534776722.155475015-0.59404274-0.0783584690.120112061-0.118300144-1.074787386-1.147923197-1.1572224861.269889065-0.259518146-0.0089086530.284198265
19298-0.454790882-0.97728529-0.205666754-0.605607262-1.087349274-0.10306615-0.60070326-0.925195234-1.458525369-0.27883792-1.367733623-0.171571073-1.09862752-0.510611565-1.05222419-1.767703451-1.164373523-0.584773473-2.047434889-0.809748910.246407059-0.67101059-0.243481298
1932482.004829680.4388831630.4550041340.0702446190.0414500850.1242225950.2355801850.2954929170.304879493-1.059557133-0.8264628981.424420804-0.289231633-0.7496845470.4937169270.101530896-0.049615539-0.269141948-0.118207862-0.002161956-0.372870073-0.674998641-0.290941668
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10445 is not tested in classification assay
Integrated Annotations for CG10445 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of alternative nuclear mRNA splicing, via spliceosomeGO:0000381inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred by curator from GO:0000381
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ATP bindingGO:0005524inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR001650
DNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10445 in FlyBase
FLIGHTClick here to see CG10445 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10445 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10445
Entrez GeneEntrez Gene page for CG10445
UniprotUniprot page for CG10445

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)